ACSL1 Aggravates Thromboinflammation by LPC/LPA Metabolic Axis in Hyperlipidemia Associated Myocardial Ischemia‐Reperfusion Injury

ACSL1 Aggravates Thromboinflammation by LPC/LPA Metabolic Axis in Hyperlipidemia Associated Myocardial Ischemia‐Reperfusion Injury

Abstract Acute myocardial infarction (AMI) is associated with well‐established metabolic risk factors, especially hyperlipidemia and obesity. Myocardial ischemia‐reperfusion injury (mIRI) significantly offsets the therapeutic efficacy of revascularization. Previous studies indicated that disrupted l...

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Bibliographic Details
Main Authors: Shuai Jiang, Xueguang Lin, Bo Chen, Gang Chen, Kristine J.S. Kwan, Jing Liu, Qi Sun, Jie Wang, Yijie Lu, Jindong Tong, Ying Deng, Bo Yu, Jingdong Tang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
ACSL1
hyperlipidemia
ischemia‐reperfusion injury
lipid metabolism
thromboinflammation
Online Access:https://doi.org/10.1002/advs.202406359
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