A Comprehensive Literature Review of Total Hip Arthroplasty (THA): Part 1—Biomaterials
The rapid advancement of materials science has revolutionized total hip arthroplasty (THA), a critical orthopedic procedure aimed at restoring mobility and improving patient quality of life. This review investigates the evolution of biomaterials used in THA, analyzing their mechanical, biological, a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-05-01
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| Series: | Journal of Functional Biomaterials |
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| Online Access: | https://www.mdpi.com/2079-4983/16/5/179 |
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| author | Chiara Morano Salvatore Garofalo Paolo Bertuccio Agata Sposato Irene Zappone Leonardo Pagnotta |
| author_facet | Chiara Morano Salvatore Garofalo Paolo Bertuccio Agata Sposato Irene Zappone Leonardo Pagnotta |
| author_sort | Chiara Morano |
| collection | DOAJ |
| description | The rapid advancement of materials science has revolutionized total hip arthroplasty (THA), a critical orthopedic procedure aimed at restoring mobility and improving patient quality of life. This review investigates the evolution of biomaterials used in THA, analyzing their mechanical, biological, and chemical properties. The study outlines the transition from early natural materials to modern metals, polymers, and ceramics, highlighting their benefits and limitations in clinical applications. Particular emphasis is placed on the development of advanced materials such as highly cross-linked polyethylene (HXLPE), zirconia-toughened alumina (ZTA), and tantalum alloys (Ta), which demonstrate enhanced biocompatibility, wear resistance, and longevity. By examining emerging trends, including bioactive coatings and nanotechnology, this paper aims to provide a comprehensive understanding of current challenges and future directions in material selection for hip prostheses, ultimately aiming to minimize annual revision rates and improve long-term outcomes. |
| format | Article |
| id | doaj-art-172ee8b8f2a24bf3a39ee136e77bb9ff |
| institution | OA Journals |
| issn | 2079-4983 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Biomaterials |
| spelling | doaj-art-172ee8b8f2a24bf3a39ee136e77bb9ff2025-08-20T01:56:24ZengMDPI AGJournal of Functional Biomaterials2079-49832025-05-0116517910.3390/jfb16050179A Comprehensive Literature Review of Total Hip Arthroplasty (THA): Part 1—BiomaterialsChiara Morano0Salvatore Garofalo1Paolo Bertuccio2Agata Sposato3Irene Zappone4Leonardo Pagnotta5Department of Mechanical, Energy and Management Engineering, University of Calabria, Via P. Bucci 44C, 87036 Rende, ItalyDepartment of Mechanical, Energy and Management Engineering, University of Calabria, Via P. Bucci 44C, 87036 Rende, ItalyDepartment of Mechanical, Energy and Management Engineering, University of Calabria, Via P. Bucci 44C, 87036 Rende, ItalyDepartment of Mechanical, Energy and Management Engineering, University of Calabria, Via P. Bucci 44C, 87036 Rende, ItalyDepartment of Mechanical, Energy and Management Engineering, University of Calabria, Via P. Bucci 44C, 87036 Rende, ItalyDepartment of Mechanical, Energy and Management Engineering, University of Calabria, Via P. Bucci 44C, 87036 Rende, ItalyThe rapid advancement of materials science has revolutionized total hip arthroplasty (THA), a critical orthopedic procedure aimed at restoring mobility and improving patient quality of life. This review investigates the evolution of biomaterials used in THA, analyzing their mechanical, biological, and chemical properties. The study outlines the transition from early natural materials to modern metals, polymers, and ceramics, highlighting their benefits and limitations in clinical applications. Particular emphasis is placed on the development of advanced materials such as highly cross-linked polyethylene (HXLPE), zirconia-toughened alumina (ZTA), and tantalum alloys (Ta), which demonstrate enhanced biocompatibility, wear resistance, and longevity. By examining emerging trends, including bioactive coatings and nanotechnology, this paper aims to provide a comprehensive understanding of current challenges and future directions in material selection for hip prostheses, ultimately aiming to minimize annual revision rates and improve long-term outcomes.https://www.mdpi.com/2079-4983/16/5/179total hip arthroplasty (THA)total hip replacement (THR)bearing surfacesbiomaterialsmaterial selection |
| spellingShingle | Chiara Morano Salvatore Garofalo Paolo Bertuccio Agata Sposato Irene Zappone Leonardo Pagnotta A Comprehensive Literature Review of Total Hip Arthroplasty (THA): Part 1—Biomaterials Journal of Functional Biomaterials total hip arthroplasty (THA) total hip replacement (THR) bearing surfaces biomaterials material selection |
| title | A Comprehensive Literature Review of Total Hip Arthroplasty (THA): Part 1—Biomaterials |
| title_full | A Comprehensive Literature Review of Total Hip Arthroplasty (THA): Part 1—Biomaterials |
| title_fullStr | A Comprehensive Literature Review of Total Hip Arthroplasty (THA): Part 1—Biomaterials |
| title_full_unstemmed | A Comprehensive Literature Review of Total Hip Arthroplasty (THA): Part 1—Biomaterials |
| title_short | A Comprehensive Literature Review of Total Hip Arthroplasty (THA): Part 1—Biomaterials |
| title_sort | comprehensive literature review of total hip arthroplasty tha part 1 biomaterials |
| topic | total hip arthroplasty (THA) total hip replacement (THR) bearing surfaces biomaterials material selection |
| url | https://www.mdpi.com/2079-4983/16/5/179 |
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