Evaluation of association between hepatitis A and Helicobacter pylori infections and routes of transmission

Previous research about coexistence of Helicobacter pylori (HP) and hepatitis A virus (HAV) infections and the factors that increase their prevalence has suggested that the route of transmission of HP infection includes oral-oral and water-foods as well as the fecal-oral route. The aim of thi...

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Main Authors: Ayten Egemen, Ozge Yilmaz, Ipek Akil, Imre Altuğlu
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2006-04-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2614
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author Ayten Egemen
Ozge Yilmaz
Ipek Akil
Imre Altuğlu
author_facet Ayten Egemen
Ozge Yilmaz
Ipek Akil
Imre Altuğlu
author_sort Ayten Egemen
collection DOAJ
description Previous research about coexistence of Helicobacter pylori (HP) and hepatitis A virus (HAV) infections and the factors that increase their prevalence has suggested that the route of transmission of HP infection includes oral-oral and water-foods as well as the fecal-oral route. The aim of this study was to evaluate the routes of transmission of HP by comparing the seroprevalences of HP and HAV in children. One hundred and two children aged 1-18 years living in rural and urban regions of Izmir were included in this study. Anti-HP IgG and anti-HAV IgG antibodies were measured via enzyme immunoassay method. Seropositivities for HP and HAV were 56.8% and 51.9%, respectively. Seroprevalence for both infections increased with increasing age. However, a significant difference could not be detected between rural and urban areas. Sex did not have a significant effect. There was no infection in 22.1% of children, while 30.8% had both of the infections. 21.1% were positive only for HAV while 26% were positive only for HP. No significant correlation between seroprevalences of HP and HAV was detected. This study suggests the existence of various other routes of transmission of HP apart from the fecal-oral route.
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publisher Hacettepe University Institute of Child Health
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spelling doaj-art-171e7c256d7447ad8251856150f790452025-08-20T02:55:24ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212006-04-01482Evaluation of association between hepatitis A and Helicobacter pylori infections and routes of transmissionAyten Egemen0Ozge YilmazIpek AkilImre AltuğluDepartment of Pediatrics, Ege University Faculty of Medicine, Izmir, Turkey. Previous research about coexistence of Helicobacter pylori (HP) and hepatitis A virus (HAV) infections and the factors that increase their prevalence has suggested that the route of transmission of HP infection includes oral-oral and water-foods as well as the fecal-oral route. The aim of this study was to evaluate the routes of transmission of HP by comparing the seroprevalences of HP and HAV in children. One hundred and two children aged 1-18 years living in rural and urban regions of Izmir were included in this study. Anti-HP IgG and anti-HAV IgG antibodies were measured via enzyme immunoassay method. Seropositivities for HP and HAV were 56.8% and 51.9%, respectively. Seroprevalence for both infections increased with increasing age. However, a significant difference could not be detected between rural and urban areas. Sex did not have a significant effect. There was no infection in 22.1% of children, while 30.8% had both of the infections. 21.1% were positive only for HAV while 26% were positive only for HP. No significant correlation between seroprevalences of HP and HAV was detected. This study suggests the existence of various other routes of transmission of HP apart from the fecal-oral route. https://turkjpediatr.org/article/view/2614
spellingShingle Ayten Egemen
Ozge Yilmaz
Ipek Akil
Imre Altuğlu
Evaluation of association between hepatitis A and Helicobacter pylori infections and routes of transmission
The Turkish Journal of Pediatrics
title Evaluation of association between hepatitis A and Helicobacter pylori infections and routes of transmission
title_full Evaluation of association between hepatitis A and Helicobacter pylori infections and routes of transmission
title_fullStr Evaluation of association between hepatitis A and Helicobacter pylori infections and routes of transmission
title_full_unstemmed Evaluation of association between hepatitis A and Helicobacter pylori infections and routes of transmission
title_short Evaluation of association between hepatitis A and Helicobacter pylori infections and routes of transmission
title_sort evaluation of association between hepatitis a and helicobacter pylori infections and routes of transmission
url https://turkjpediatr.org/article/view/2614
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AT ipekakil evaluationofassociationbetweenhepatitisaandhelicobacterpyloriinfectionsandroutesoftransmission
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