Ruptured Ectopic Pregnancy Misdiagnosed with Ruptured Corpus Luteum: A Case Report and Literature Review

Ectopic pregnancy can be mistakenly reported as a ruptured corpus luteum. A 22-year-old woman was initially misdiagnosed with a ruptured corpus luteum and treated with analgesics at a local clinic. Persistent symptoms led her to our hospital, where a pelvic ultrasound revealed a 5.2 cm ×4.8 cm hemat...

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Main Authors: Wing Yu Sharon Siu, Dah-Ching Ding
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Gynecology and Minimally Invasive Therapy
Subjects:
Online Access:https://journals.lww.com/10.4103/gmit.GMIT-D-24-00006
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author Wing Yu Sharon Siu
Dah-Ching Ding
author_facet Wing Yu Sharon Siu
Dah-Ching Ding
author_sort Wing Yu Sharon Siu
collection DOAJ
description Ectopic pregnancy can be mistakenly reported as a ruptured corpus luteum. A 22-year-old woman was initially misdiagnosed with a ruptured corpus luteum and treated with analgesics at a local clinic. Persistent symptoms led her to our hospital, where a pelvic ultrasound revealed a 5.2 cm ×4.8 cm hematoma. Despite the significant hematoma, her vital signs were stable. A urine pregnancy test was positive, β-hCG was 5553 mIU/mL, and hemoglobin (Hb) was 6.3 g/dL. After a blood transfusion, methotrexate (MTX) was administered, reducing β-hCG to 4428 mIU/mL by day 5. Four weeks later, β-hCG was 723.6 mIU/mL, and a second MTX dose was given. Three weeks later, β-hCG was 4.7 mIU/mL, and Hb was 12.4 g/dL. In conclusion, a “wait-and-see” approach with serial hCG testing and repeated ultrasounds is recommended in unclear cases.
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spelling doaj-art-1715fd1e37384ab5b0f47c4c2eb5c8b32025-08-20T02:34:40ZengWolters Kluwer Medknow PublicationsGynecology and Minimally Invasive Therapy2213-30702025-04-0114218919210.4103/gmit.GMIT-D-24-00006Ruptured Ectopic Pregnancy Misdiagnosed with Ruptured Corpus Luteum: A Case Report and Literature ReviewWing Yu Sharon SiuDah-Ching DingEctopic pregnancy can be mistakenly reported as a ruptured corpus luteum. A 22-year-old woman was initially misdiagnosed with a ruptured corpus luteum and treated with analgesics at a local clinic. Persistent symptoms led her to our hospital, where a pelvic ultrasound revealed a 5.2 cm ×4.8 cm hematoma. Despite the significant hematoma, her vital signs were stable. A urine pregnancy test was positive, β-hCG was 5553 mIU/mL, and hemoglobin (Hb) was 6.3 g/dL. After a blood transfusion, methotrexate (MTX) was administered, reducing β-hCG to 4428 mIU/mL by day 5. Four weeks later, β-hCG was 723.6 mIU/mL, and a second MTX dose was given. Three weeks later, β-hCG was 4.7 mIU/mL, and Hb was 12.4 g/dL. In conclusion, a “wait-and-see” approach with serial hCG testing and repeated ultrasounds is recommended in unclear cases.https://journals.lww.com/10.4103/gmit.GMIT-D-24-00006case reportcorpus luteumectopic pregnancyhematomamethotrexateruptured
spellingShingle Wing Yu Sharon Siu
Dah-Ching Ding
Ruptured Ectopic Pregnancy Misdiagnosed with Ruptured Corpus Luteum: A Case Report and Literature Review
Gynecology and Minimally Invasive Therapy
case report
corpus luteum
ectopic pregnancy
hematoma
methotrexate
ruptured
title Ruptured Ectopic Pregnancy Misdiagnosed with Ruptured Corpus Luteum: A Case Report and Literature Review
title_full Ruptured Ectopic Pregnancy Misdiagnosed with Ruptured Corpus Luteum: A Case Report and Literature Review
title_fullStr Ruptured Ectopic Pregnancy Misdiagnosed with Ruptured Corpus Luteum: A Case Report and Literature Review
title_full_unstemmed Ruptured Ectopic Pregnancy Misdiagnosed with Ruptured Corpus Luteum: A Case Report and Literature Review
title_short Ruptured Ectopic Pregnancy Misdiagnosed with Ruptured Corpus Luteum: A Case Report and Literature Review
title_sort ruptured ectopic pregnancy misdiagnosed with ruptured corpus luteum a case report and literature review
topic case report
corpus luteum
ectopic pregnancy
hematoma
methotrexate
ruptured
url https://journals.lww.com/10.4103/gmit.GMIT-D-24-00006
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AT dahchingding rupturedectopicpregnancymisdiagnosedwithrupturedcorpusluteumacasereportandliteraturereview