Pivotal Role of Mediterranean Dietary Regimen in the Increase of Serum Magnesium Concentration in Patients with Coronary Artery Disease

Background. Recent studies confirmed cardioprotective role of intravenous magnesium for the prevention of cardiac events, but effect of dietary intake of this mineral via recommended dietary regimens on control and inhibition of coronary artery disease (CAD) risk factors has been questioned. The aim...

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Main Authors: Nimah Bahreini, Mojgan Gharipour, Hossein Khosravi-Boroujeni, Hojjat Rouhi-Boroujeni, Afshin Shiranian, Amin Salehi-Abargouei, GholamReza Sharifzadeh
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Nutrition and Metabolism
Online Access:http://dx.doi.org/10.1155/2013/431070
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author Nimah Bahreini
Mojgan Gharipour
Hossein Khosravi-Boroujeni
Hojjat Rouhi-Boroujeni
Afshin Shiranian
Amin Salehi-Abargouei
GholamReza Sharifzadeh
author_facet Nimah Bahreini
Mojgan Gharipour
Hossein Khosravi-Boroujeni
Hojjat Rouhi-Boroujeni
Afshin Shiranian
Amin Salehi-Abargouei
GholamReza Sharifzadeh
author_sort Nimah Bahreini
collection DOAJ
description Background. Recent studies confirmed cardioprotective role of intravenous magnesium for the prevention of cardiac events, but effect of dietary intake of this mineral via recommended dietary regimens on control and inhibition of coronary artery disease (CAD) risk factors has been questioned. The aim of the present study was to determine effect of Mediterranean dietary approach on serum magnesium concentration among Iranian patients with CAD. Method. Baseline characteristics and clinical data of 102 consecutive patients with the diagnosis of CAD and candidates for isolated coronary artery bypass surgery were entered into the study. Laboratory parameters especially serum magnesium concentration were measured after 12–14 h of overnight fasting and before operation. Nutritional status was assessed by food frequency questionnaire and the diet score was calculated on the basis of Mediterranean diet quality index (Med-DQI). Results. No significant differences were found in the concentrations of albumin, last fasting blood sugar, last creatinine, and lipid profiles between the groups with Mediterranean dietary score < 5 and the group with higher dietary score; however, serum magnesium concentration in the first group was higher than that in the group with higher dietary score. Linear multivariate regression analysis showed that the lower Mediterranean dietary score was a predictor for serum magnesium concentration after adjusting for confounders. Conclusion. Taking Mediterranean dietary regimen can be associated with increased level of serum magnesium concentration, and thus this regimen can be cardioprotective because of its effects on serum magnesium.
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spelling doaj-art-1705978f1f1d4dfa9be564b9322e6dcb2025-08-20T03:54:33ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322013-01-01201310.1155/2013/431070431070Pivotal Role of Mediterranean Dietary Regimen in the Increase of Serum Magnesium Concentration in Patients with Coronary Artery DiseaseNimah Bahreini0Mojgan Gharipour1Hossein Khosravi-Boroujeni2Hojjat Rouhi-Boroujeni3Afshin Shiranian4Amin Salehi-Abargouei5GholamReza Sharifzadeh6Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Metabolic Syndrome, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranFood Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, IranMedical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, IranFood Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, IranFood Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, IranHealth Research Centers of School of Health, Birjand University of Medical Sciences, Birjand, IranBackground. Recent studies confirmed cardioprotective role of intravenous magnesium for the prevention of cardiac events, but effect of dietary intake of this mineral via recommended dietary regimens on control and inhibition of coronary artery disease (CAD) risk factors has been questioned. The aim of the present study was to determine effect of Mediterranean dietary approach on serum magnesium concentration among Iranian patients with CAD. Method. Baseline characteristics and clinical data of 102 consecutive patients with the diagnosis of CAD and candidates for isolated coronary artery bypass surgery were entered into the study. Laboratory parameters especially serum magnesium concentration were measured after 12–14 h of overnight fasting and before operation. Nutritional status was assessed by food frequency questionnaire and the diet score was calculated on the basis of Mediterranean diet quality index (Med-DQI). Results. No significant differences were found in the concentrations of albumin, last fasting blood sugar, last creatinine, and lipid profiles between the groups with Mediterranean dietary score < 5 and the group with higher dietary score; however, serum magnesium concentration in the first group was higher than that in the group with higher dietary score. Linear multivariate regression analysis showed that the lower Mediterranean dietary score was a predictor for serum magnesium concentration after adjusting for confounders. Conclusion. Taking Mediterranean dietary regimen can be associated with increased level of serum magnesium concentration, and thus this regimen can be cardioprotective because of its effects on serum magnesium.http://dx.doi.org/10.1155/2013/431070
spellingShingle Nimah Bahreini
Mojgan Gharipour
Hossein Khosravi-Boroujeni
Hojjat Rouhi-Boroujeni
Afshin Shiranian
Amin Salehi-Abargouei
GholamReza Sharifzadeh
Pivotal Role of Mediterranean Dietary Regimen in the Increase of Serum Magnesium Concentration in Patients with Coronary Artery Disease
Journal of Nutrition and Metabolism
title Pivotal Role of Mediterranean Dietary Regimen in the Increase of Serum Magnesium Concentration in Patients with Coronary Artery Disease
title_full Pivotal Role of Mediterranean Dietary Regimen in the Increase of Serum Magnesium Concentration in Patients with Coronary Artery Disease
title_fullStr Pivotal Role of Mediterranean Dietary Regimen in the Increase of Serum Magnesium Concentration in Patients with Coronary Artery Disease
title_full_unstemmed Pivotal Role of Mediterranean Dietary Regimen in the Increase of Serum Magnesium Concentration in Patients with Coronary Artery Disease
title_short Pivotal Role of Mediterranean Dietary Regimen in the Increase of Serum Magnesium Concentration in Patients with Coronary Artery Disease
title_sort pivotal role of mediterranean dietary regimen in the increase of serum magnesium concentration in patients with coronary artery disease
url http://dx.doi.org/10.1155/2013/431070
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