Meta-Analysis of Brain Structure in Magnetic Resonance Imaging Studies of Adolescents With Schizophrenia

Conclusions: Our study indicates that there are extensive structural abnormalities in the brain regions of adolescent schizophrenics, especially within cortical structures. Patients with either COS or non-first-episode schizophrenia who may have received antipsychotic medication also exhibited exten...

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Bibliographic Details
Main Authors: Mi Yang, Di Kong, Jialong Huang, Yanqing Huang, Yuting Sun, Zezhi Li
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Mental Illness
Online Access:http://dx.doi.org/10.1155/mij/6631226
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Summary:Conclusions: Our study indicates that there are extensive structural abnormalities in the brain regions of adolescent schizophrenics, especially within cortical structures. Patients with either COS or non-first-episode schizophrenia who may have received antipsychotic medication also exhibited extensive structural brain abnormalities. The thalamus, lateral ventricles, and putamen may be crucial biological markers of structural brain abnormalities in adolescent schizophrenia, providing a basis for exploring the pathological mechanisms underlying the disease, as well as essential targets for early diagnosis and treatments.
ISSN:2036-7465