Oral Bacteria of Children with Turner Syndrome
Aim:Turner syndrome (TS) is a genetic disorder caused by a numerical or structural aberration of the X chromosome, which is associated with a female phenotype. Concerning oral status, several studies have revealed that girls with TS have dental anomalies and periodontal problems. The aim of this stu...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2019-03-01
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| Series: | Journal of Pediatric Research |
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http://jpedres.org/archives/archive-detail/article-preview/oral-bacteria-of-children-with-turner-syndrome/26283
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| author | Gülcan Ünsal Nursen Topçuoğlu Yeliz Güven Şükran Poyrazoğlu Güven Külekçi Oya Aktören |
| author_facet | Gülcan Ünsal Nursen Topçuoğlu Yeliz Güven Şükran Poyrazoğlu Güven Külekçi Oya Aktören |
| author_sort | Gülcan Ünsal |
| collection | DOAJ |
| description | Aim:Turner syndrome (TS) is a genetic disorder caused by a numerical or structural aberration of the X chromosome, which is associated with a female phenotype. Concerning oral status, several studies have revealed that girls with TS have dental anomalies and periodontal problems. The aim of this study was to evaluate the effects of oral bacteria on caries prevalence and periodontal status in pediatric patients with TS.Materials and Methods:Twenty TS patients and 17 healthy girls were examined for cariological and periodontal status. The levels of mutans streptococci (MS), lactobacilli (LB), yeast and 10 different periodontal bacteria were determined by using culture and microarray techniques in children’s stimulated saliva samples.Results:There was no difference in salivary flow rate and buffering capacity, decayed-missing-filled teeth, MS, LB, or yeast levels between the groups. Plaque index and gingival index levels were significantly higher in the Turner group and dft was significantly higher in the control group (p<0.05). As a result, microarray analysis, Prevotella intermedia, Fusobacterium nucleatum, Eikenella corrodens, Aggregatibacter actinomycetemcomitans, Actinomyces viscosus were detected at high levels in the Turner group (p<0.05).Conclusion:Besides dental and craniofacial anomalies, clinicians should be alert to the early diagnosis and treatment of periodontal problems in patients with TS. |
| format | Article |
| id | doaj-art-1700e3544e6b4d0fb7f76f728c5aaddd |
| institution | Kabale University |
| issn | 2147-9445 2587-2478 |
| language | English |
| publishDate | 2019-03-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Journal of Pediatric Research |
| spelling | doaj-art-1700e3544e6b4d0fb7f76f728c5aaddd2025-08-20T03:54:33ZengGalenos Publishing HouseJournal of Pediatric Research2147-94452587-24782019-03-0161445010.4274/jpr.galenos.2018.4032713049054Oral Bacteria of Children with Turner SyndromeGülcan Ünsal0Nursen Topçuoğlu1Yeliz Güven2Şükran Poyrazoğlu3Güven Külekçi4Oya Aktören5 İstanbul University Faculty of Dentistry, Department of Pediatric Dentistry, İstanbul, Turkey stanbul University Faculty of Dentistry, Department of Oral Microbiology, İstanbul, Turkey İstanbul University Faculty of Dentistry, Department of Pediatric Dentistry, İstanbul, Turkey İstanbul University Faculty of Medicine, Deparment of Pediatric Endocrinology and Metabolism, İstanbul, Turkey stanbul University Faculty of Dentistry, Department of Oral Microbiology, İstanbul, Turkey İstanbul University Faculty of Dentistry, Department of Pediatric Dentistry, İstanbul, Turkey Aim:Turner syndrome (TS) is a genetic disorder caused by a numerical or structural aberration of the X chromosome, which is associated with a female phenotype. Concerning oral status, several studies have revealed that girls with TS have dental anomalies and periodontal problems. The aim of this study was to evaluate the effects of oral bacteria on caries prevalence and periodontal status in pediatric patients with TS.Materials and Methods:Twenty TS patients and 17 healthy girls were examined for cariological and periodontal status. The levels of mutans streptococci (MS), lactobacilli (LB), yeast and 10 different periodontal bacteria were determined by using culture and microarray techniques in children’s stimulated saliva samples.Results:There was no difference in salivary flow rate and buffering capacity, decayed-missing-filled teeth, MS, LB, or yeast levels between the groups. Plaque index and gingival index levels were significantly higher in the Turner group and dft was significantly higher in the control group (p<0.05). As a result, microarray analysis, Prevotella intermedia, Fusobacterium nucleatum, Eikenella corrodens, Aggregatibacter actinomycetemcomitans, Actinomyces viscosus were detected at high levels in the Turner group (p<0.05).Conclusion:Besides dental and craniofacial anomalies, clinicians should be alert to the early diagnosis and treatment of periodontal problems in patients with TS. http://jpedres.org/archives/archive-detail/article-preview/oral-bacteria-of-children-with-turner-syndrome/26283 Turner syndromemicroarray analysisoral bacteria |
| spellingShingle | Gülcan Ünsal Nursen Topçuoğlu Yeliz Güven Şükran Poyrazoğlu Güven Külekçi Oya Aktören Oral Bacteria of Children with Turner Syndrome Journal of Pediatric Research Turner syndrome microarray analysis oral bacteria |
| title | Oral Bacteria of Children with Turner Syndrome |
| title_full | Oral Bacteria of Children with Turner Syndrome |
| title_fullStr | Oral Bacteria of Children with Turner Syndrome |
| title_full_unstemmed | Oral Bacteria of Children with Turner Syndrome |
| title_short | Oral Bacteria of Children with Turner Syndrome |
| title_sort | oral bacteria of children with turner syndrome |
| topic | Turner syndrome microarray analysis oral bacteria |
| url |
http://jpedres.org/archives/archive-detail/article-preview/oral-bacteria-of-children-with-turner-syndrome/26283
|
| work_keys_str_mv | AT gulcanunsal oralbacteriaofchildrenwithturnersyndrome AT nursentopcuoglu oralbacteriaofchildrenwithturnersyndrome AT yelizguven oralbacteriaofchildrenwithturnersyndrome AT sukranpoyrazoglu oralbacteriaofchildrenwithturnersyndrome AT guvenkulekci oralbacteriaofchildrenwithturnersyndrome AT oyaaktoren oralbacteriaofchildrenwithturnersyndrome |