Recent advances of SNHG in regulating mesenchymal stem cell osteogenic differentiation

Bone healing and bore regeneration are complex processes in maintaining normal bone homeostasis. Mesenchymal stem cells are main resource of osteoblasts that are responsible for bone formation. Long noncoding RNA (lncRNA) is emerging as important regulatory role in the osteogenic differentiation of...

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Main Authors: HUANG Jie, WANG Zuolin
Format: Article
Language:zho
Published: Editorial Office of Journal of Oral and Maxillofacial Surgery 2024-08-01
Series:Kouqiang hemian waike zazhi
Subjects:
Online Access:https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.04.009
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author HUANG Jie
WANG Zuolin
author_facet HUANG Jie
WANG Zuolin
author_sort HUANG Jie
collection DOAJ
description Bone healing and bore regeneration are complex processes in maintaining normal bone homeostasis. Mesenchymal stem cells are main resource of osteoblasts that are responsible for bone formation. Long noncoding RNA (lncRNA) is emerging as important regulatory role in the osteogenic differentiation of mesenchymal stem cells, in which lncRNA small nucleolar RNA host gene (SNHG) has been shown to be participated in mesenchymal stem cell osteogenic differentiation via various mechanisms, promising to be a new therapeutic target in bone metabolism and bone regeneration therapy. Herein, this article aims to review the biological functions and emerging mechanisms of SNHG involved in the mesenchymal stem cell osteogenic differentiation.
format Article
id doaj-art-16f5e9311c5244dc962cf1d8d6ac8b1d
institution Kabale University
issn 1005-4979
language zho
publishDate 2024-08-01
publisher Editorial Office of Journal of Oral and Maxillofacial Surgery
record_format Article
series Kouqiang hemian waike zazhi
spelling doaj-art-16f5e9311c5244dc962cf1d8d6ac8b1d2025-08-25T06:11:14ZzhoEditorial Office of Journal of Oral and Maxillofacial SurgeryKouqiang hemian waike zazhi1005-49792024-08-0134430630910.12439/kqhm.1005-4979.2024.04.009Recent advances of SNHG in regulating mesenchymal stem cell osteogenic differentiationHUANG Jie0WANG Zuolin1Shanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Oral Implantology, Stomatological Hospital and Dental School, Tongji University, Shanghai 200072, ChinaShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Oral Implantology, Stomatological Hospital and Dental School, Tongji University, Shanghai 200072, ChinaBone healing and bore regeneration are complex processes in maintaining normal bone homeostasis. Mesenchymal stem cells are main resource of osteoblasts that are responsible for bone formation. Long noncoding RNA (lncRNA) is emerging as important regulatory role in the osteogenic differentiation of mesenchymal stem cells, in which lncRNA small nucleolar RNA host gene (SNHG) has been shown to be participated in mesenchymal stem cell osteogenic differentiation via various mechanisms, promising to be a new therapeutic target in bone metabolism and bone regeneration therapy. Herein, this article aims to review the biological functions and emerging mechanisms of SNHG involved in the mesenchymal stem cell osteogenic differentiation.https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.04.009bone regenerationsmall nucleolar rna host genelong noncoding rna
spellingShingle HUANG Jie
WANG Zuolin
Recent advances of SNHG in regulating mesenchymal stem cell osteogenic differentiation
Kouqiang hemian waike zazhi
bone regeneration
small nucleolar rna host gene
long noncoding rna
title Recent advances of SNHG in regulating mesenchymal stem cell osteogenic differentiation
title_full Recent advances of SNHG in regulating mesenchymal stem cell osteogenic differentiation
title_fullStr Recent advances of SNHG in regulating mesenchymal stem cell osteogenic differentiation
title_full_unstemmed Recent advances of SNHG in regulating mesenchymal stem cell osteogenic differentiation
title_short Recent advances of SNHG in regulating mesenchymal stem cell osteogenic differentiation
title_sort recent advances of snhg in regulating mesenchymal stem cell osteogenic differentiation
topic bone regeneration
small nucleolar rna host gene
long noncoding rna
url https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.04.009
work_keys_str_mv AT huangjie recentadvancesofsnhginregulatingmesenchymalstemcellosteogenicdifferentiation
AT wangzuolin recentadvancesofsnhginregulatingmesenchymalstemcellosteogenicdifferentiation