Anti-Aging Potential of Avocado Oil via Its Antioxidant Effects
Aging is a process characterized by tissue degeneration, increased susceptibility to chronic degenerative diseases, infections, and the appearance of neoplasms, which leads to disability and a reduction in the length and quality of life. This phenomenon is the result of the convergence of multiple p...
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MDPI AG
2025-02-01
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| Series: | Pharmaceuticals |
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| Online Access: | https://www.mdpi.com/1424-8247/18/2/246 |
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| author | Olin Torres-Isidro Marcela González-Montoya Manuel Alejandro Vargas-Vargas Ulises Florian-Rodriguez Claudia Isabel García-Berumen Rocío Montoya-Pérez Alfredo Saavedra-Molina Elizabeth Calderón-Cortés Alain Raimundo Rodríguez-Orozco Christian Cortés-Rojo |
| author_facet | Olin Torres-Isidro Marcela González-Montoya Manuel Alejandro Vargas-Vargas Ulises Florian-Rodriguez Claudia Isabel García-Berumen Rocío Montoya-Pérez Alfredo Saavedra-Molina Elizabeth Calderón-Cortés Alain Raimundo Rodríguez-Orozco Christian Cortés-Rojo |
| author_sort | Olin Torres-Isidro |
| collection | DOAJ |
| description | Aging is a process characterized by tissue degeneration, increased susceptibility to chronic degenerative diseases, infections, and the appearance of neoplasms, which leads to disability and a reduction in the length and quality of life. This phenomenon is the result of the convergence of multiple processes, including mitochondrial dysfunction, fibrosis, inflammation, dysregulation of cell death processes, and immunosenescence. These processes have as their point of convergence an increase in the production of ROS. Avocado oil (<i>Persea americana</i> Mill.) contains a diverse array of bioactive compounds, including oleic acid, phytosterols, chlorophylls, xanthones, xanthines, and carotenoids. These bioactive compounds have the capacity to modulate the excessive production of ROS, thereby reducing the progression of age-related diseases and extending lifespan in experimental models of aging. In addition, several studies have demonstrated the efficacy of avocado oil in mitigating age-related diseases, including hypertension; insulin resistance; diabetes; non-alcoholic liver disease; and degenerative processes such as hearing loss, cognitive decline, neurodegeneration, and impaired wound healing. In light of these findings, it is hypothesized that avocado oil is a promising agent capable of promoting healthspan in later stages of life owing to its direct antioxidant actions and the activation of pathways that enhance endogenous antioxidant levels. |
| format | Article |
| id | doaj-art-16ef3c1e55fe4bafbe61e176543c6c71 |
| institution | DOAJ |
| issn | 1424-8247 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceuticals |
| spelling | doaj-art-16ef3c1e55fe4bafbe61e176543c6c712025-08-20T03:12:12ZengMDPI AGPharmaceuticals1424-82472025-02-0118224610.3390/ph18020246Anti-Aging Potential of Avocado Oil via Its Antioxidant EffectsOlin Torres-Isidro0Marcela González-Montoya1Manuel Alejandro Vargas-Vargas2Ulises Florian-Rodriguez3Claudia Isabel García-Berumen4Rocío Montoya-Pérez5Alfredo Saavedra-Molina6Elizabeth Calderón-Cortés7Alain Raimundo Rodríguez-Orozco8Christian Cortés-Rojo9Instituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58030, Michoacán, MexicoInstituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58030, Michoacán, MexicoInstituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58030, Michoacán, MexicoFacultad de Químico Farmacobiología, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58240, Michoacán, MexicoInstituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58030, Michoacán, MexicoInstituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58030, Michoacán, MexicoInstituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58030, Michoacán, MexicoFacultad de Enfermería, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58260, Michoacán, MexicoFacultad de Ciencias Médicas y Biológicas “Dr. Ignacio Chávez”, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58020, Michoacán, MexicoInstituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58030, Michoacán, MexicoAging is a process characterized by tissue degeneration, increased susceptibility to chronic degenerative diseases, infections, and the appearance of neoplasms, which leads to disability and a reduction in the length and quality of life. This phenomenon is the result of the convergence of multiple processes, including mitochondrial dysfunction, fibrosis, inflammation, dysregulation of cell death processes, and immunosenescence. These processes have as their point of convergence an increase in the production of ROS. Avocado oil (<i>Persea americana</i> Mill.) contains a diverse array of bioactive compounds, including oleic acid, phytosterols, chlorophylls, xanthones, xanthines, and carotenoids. These bioactive compounds have the capacity to modulate the excessive production of ROS, thereby reducing the progression of age-related diseases and extending lifespan in experimental models of aging. In addition, several studies have demonstrated the efficacy of avocado oil in mitigating age-related diseases, including hypertension; insulin resistance; diabetes; non-alcoholic liver disease; and degenerative processes such as hearing loss, cognitive decline, neurodegeneration, and impaired wound healing. In light of these findings, it is hypothesized that avocado oil is a promising agent capable of promoting healthspan in later stages of life owing to its direct antioxidant actions and the activation of pathways that enhance endogenous antioxidant levels.https://www.mdpi.com/1424-8247/18/2/246<i>Persea americana</i>aginglifespanhealthspansenescencephytosterols |
| spellingShingle | Olin Torres-Isidro Marcela González-Montoya Manuel Alejandro Vargas-Vargas Ulises Florian-Rodriguez Claudia Isabel García-Berumen Rocío Montoya-Pérez Alfredo Saavedra-Molina Elizabeth Calderón-Cortés Alain Raimundo Rodríguez-Orozco Christian Cortés-Rojo Anti-Aging Potential of Avocado Oil via Its Antioxidant Effects Pharmaceuticals <i>Persea americana</i> aging lifespan healthspan senescence phytosterols |
| title | Anti-Aging Potential of Avocado Oil via Its Antioxidant Effects |
| title_full | Anti-Aging Potential of Avocado Oil via Its Antioxidant Effects |
| title_fullStr | Anti-Aging Potential of Avocado Oil via Its Antioxidant Effects |
| title_full_unstemmed | Anti-Aging Potential of Avocado Oil via Its Antioxidant Effects |
| title_short | Anti-Aging Potential of Avocado Oil via Its Antioxidant Effects |
| title_sort | anti aging potential of avocado oil via its antioxidant effects |
| topic | <i>Persea americana</i> aging lifespan healthspan senescence phytosterols |
| url | https://www.mdpi.com/1424-8247/18/2/246 |
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