Extracellular vesicles as novel therapeutic targets and diagnosis markers
Extracellular vesicles (EVs) are membranous vesicles secreted from cells to the outside and are widely present in body fluids. The most commonly used method to isolate EVs is ultracentrifugation. EVs contain lipids, proteins, genetic material, and organelles, which can be used as communication carri...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Extracellular Vesicle |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773041722000129 |
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| author | Yu Zhang Weiliang Wu Xiangbin Pan Yanli Wang Chengjie Wu Lin Lu Xi-Yong Yu Yangxin Li |
| author_facet | Yu Zhang Weiliang Wu Xiangbin Pan Yanli Wang Chengjie Wu Lin Lu Xi-Yong Yu Yangxin Li |
| author_sort | Yu Zhang |
| collection | DOAJ |
| description | Extracellular vesicles (EVs) are membranous vesicles secreted from cells to the outside and are widely present in body fluids. The most commonly used method to isolate EVs is ultracentrifugation. EVs contain lipids, proteins, genetic material, and organelles, which can be used as communication carriers between different cells and potential disease biomarkers. EVs secreted by different cells (cancer cells, adipocytes, mesenchymal stem cells, immune cells et al.) play different functions. With the development of technology, EVs can also be engineered to deliver drugs. EVs also play an important role in the progression, prevention, diagnosis, and treatment of Corona Virus Disease 2019 (COVID-19). |
| format | Article |
| id | doaj-art-16cfe2fa053e4dbfb89036222fba56da |
| institution | OA Journals |
| issn | 2773-0417 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Extracellular Vesicle |
| spelling | doaj-art-16cfe2fa053e4dbfb89036222fba56da2025-08-20T02:02:58ZengElsevierExtracellular Vesicle2773-04172022-12-01110001710.1016/j.vesic.2022.100017Extracellular vesicles as novel therapeutic targets and diagnosis markersYu Zhang0Weiliang Wu1Xiangbin Pan2Yanli Wang3Chengjie Wu4Lin Lu5Xi-Yong Yu6Yangxin Li7Institute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou Jiangsu 215123, PR ChinaInstitute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou Jiangsu 215123, PR ChinaDepartment of Structural Heart Disease, National Center for Cardiovascular Disease, China & Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, Key Laboratory of Cardiovascular Appratus Innovation, Beijing 100037, PR ChinaInstitute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou Jiangsu 215123, PR ChinaInstitute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou Jiangsu 215123, PR ChinaInstitute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou Jiangsu 215123, PR ChinaKey Laboratory of Molecular Target & Clinical Pharmacology and the NMPA & State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong 511436, PR ChinaInstitute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital and Medical College of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou Jiangsu 215123, PR China; Corresponding author.Extracellular vesicles (EVs) are membranous vesicles secreted from cells to the outside and are widely present in body fluids. The most commonly used method to isolate EVs is ultracentrifugation. EVs contain lipids, proteins, genetic material, and organelles, which can be used as communication carriers between different cells and potential disease biomarkers. EVs secreted by different cells (cancer cells, adipocytes, mesenchymal stem cells, immune cells et al.) play different functions. With the development of technology, EVs can also be engineered to deliver drugs. EVs also play an important role in the progression, prevention, diagnosis, and treatment of Corona Virus Disease 2019 (COVID-19).http://www.sciencedirect.com/science/article/pii/S2773041722000129Extracellular vesiclesncRNADiagnosisTherapeutic targets |
| spellingShingle | Yu Zhang Weiliang Wu Xiangbin Pan Yanli Wang Chengjie Wu Lin Lu Xi-Yong Yu Yangxin Li Extracellular vesicles as novel therapeutic targets and diagnosis markers Extracellular Vesicle Extracellular vesicles ncRNA Diagnosis Therapeutic targets |
| title | Extracellular vesicles as novel therapeutic targets and diagnosis markers |
| title_full | Extracellular vesicles as novel therapeutic targets and diagnosis markers |
| title_fullStr | Extracellular vesicles as novel therapeutic targets and diagnosis markers |
| title_full_unstemmed | Extracellular vesicles as novel therapeutic targets and diagnosis markers |
| title_short | Extracellular vesicles as novel therapeutic targets and diagnosis markers |
| title_sort | extracellular vesicles as novel therapeutic targets and diagnosis markers |
| topic | Extracellular vesicles ncRNA Diagnosis Therapeutic targets |
| url | http://www.sciencedirect.com/science/article/pii/S2773041722000129 |
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