Localized Castleman’s Disease in the Breast in a Young Woman

Castleman’s disease (CD) is a rare lymphoproliferative disorder of unknown etiology. It typically occurs in adulthood but it may also develop in childhood. Clinically, this disease may be classified as localized (unicentric) or systemic (multicentric). Six cases of breast CD have been described in t...

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Main Authors: Rafael Parra-Medina, José Ismael Guio, Patricia López-Correa
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2016/8413987
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author Rafael Parra-Medina
José Ismael Guio
Patricia López-Correa
author_facet Rafael Parra-Medina
José Ismael Guio
Patricia López-Correa
author_sort Rafael Parra-Medina
collection DOAJ
description Castleman’s disease (CD) is a rare lymphoproliferative disorder of unknown etiology. It typically occurs in adulthood but it may also develop in childhood. Clinically, this disease may be classified as localized (unicentric) or systemic (multicentric). Six cases of breast CD have been described in the literature, and all have been reported in adults. Herein we describe the case of a 15-year-old female who presented with a slow-growing tumor in the right breast. The tumor was excised and histopathological examination demonstrated hyaline vascular variant CD. After two years of follow-up, the patient was asymptomatic without evidence of cervical or axillary lymphadenopathy.
format Article
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publishDate 2016-01-01
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series Case Reports in Pathology
spelling doaj-art-16c592637d5f442888340f5f5e3888132025-08-20T02:02:33ZengWileyCase Reports in Pathology2090-67812090-679X2016-01-01201610.1155/2016/84139878413987Localized Castleman’s Disease in the Breast in a Young WomanRafael Parra-Medina0José Ismael Guio1Patricia López-Correa2Fundación Universitaria de Ciencias de la Salud, Bogotá, ColombiaFundación Universitaria de Ciencias de la Salud, Bogotá, ColombiaFundación Universitaria de Ciencias de la Salud, Bogotá, ColombiaCastleman’s disease (CD) is a rare lymphoproliferative disorder of unknown etiology. It typically occurs in adulthood but it may also develop in childhood. Clinically, this disease may be classified as localized (unicentric) or systemic (multicentric). Six cases of breast CD have been described in the literature, and all have been reported in adults. Herein we describe the case of a 15-year-old female who presented with a slow-growing tumor in the right breast. The tumor was excised and histopathological examination demonstrated hyaline vascular variant CD. After two years of follow-up, the patient was asymptomatic without evidence of cervical or axillary lymphadenopathy.http://dx.doi.org/10.1155/2016/8413987
spellingShingle Rafael Parra-Medina
José Ismael Guio
Patricia López-Correa
Localized Castleman’s Disease in the Breast in a Young Woman
Case Reports in Pathology
title Localized Castleman’s Disease in the Breast in a Young Woman
title_full Localized Castleman’s Disease in the Breast in a Young Woman
title_fullStr Localized Castleman’s Disease in the Breast in a Young Woman
title_full_unstemmed Localized Castleman’s Disease in the Breast in a Young Woman
title_short Localized Castleman’s Disease in the Breast in a Young Woman
title_sort localized castleman s disease in the breast in a young woman
url http://dx.doi.org/10.1155/2016/8413987
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