Activation of autophagy with PF-06409577 alleviates heatstroke-induced organ injury

Activation of autophagy with PF-06409577 alleviates heatstroke-induced organ injury

Heat waves are a significant environmental issue threatening global human health. Extreme temperatures can lead to various heat-related illnesses, with heatstroke being among the most severe. Currently, there are no effective treatments to mitigate the multi-organ damage caused by heatstroke. We fou...

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Bibliographic Details
Main Authors: Wei Zhang, Huajing Zeng, Siyu Xie, Cheng Yu, Meina Zhang, Qiuyan Chen, Huiyue Dong, Hui Zhang, Hao Lin, Nengjing Zheng, Lin Zhu, Jun Lu
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Environment International
Subjects:
Heatstroke
Autophagy
PF-06409577
Cell death
Organ damage
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412025000364
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