Basement membrane perforations guide anterior–posterior axis formation
Abstract Establishment of the anterior-posterior (AP) axis is a critical symmetry-breaking event in mammalian development. In mice, this process involves the directed migration of the distal visceral endoderm (DVE). Here, we use targeted perturbations to demonstrate that asymmetric perforations in t...
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| Main Authors: | Dong-Yuan Chen, Nikolas H. Claussen, Shiny Titus, Wenqi Hu, Bailey A. T. Weatherbee, Rachel S. Mandelbaum, Richard T. Scott Jr, Emre Seli, Sebastian J. Streichan, Magdalena Zernicka-Goetz |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-61441-6 |
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