In vitro Ingavirin® Efficacy Against Adenoviral Infection Pathogen
The experimental investigation of the Ingavirin® antiviral effect showed that in concentrations of 200 and 100 mcg/ml it totally protected the cells from the cytopathic action of the virus, when added before the inoculation of the HeLa cell culture. After a tenfold decrease of the infective dose (up...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC "Publishing House OKI"
2020-05-01
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| Series: | Антибиотики и Химиотерапия |
| Subjects: | |
| Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/247 |
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| Summary: | The experimental investigation of the Ingavirin® antiviral effect showed that in concentrations of 200 and 100 mcg/ml it totally protected the cells from the cytopathic action of the virus, when added before the inoculation of the HeLa cell culture. After a tenfold decrease of the infective dose (up to 0.001 CPD50/cell), the inhibition of the virus cytopathic effect by Ingavirin® amounted to 100% in all the tested concentrations (including the low ones) added either before or after the culture contamination. Ingavirin® was efficient in inhibition of the adenovirus type 5 reproduction in the HeLa cell culture. |
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| ISSN: | 0235-2990 |