Gastric Follicular Lymphomas Presenting as Subepithelial Tumors: Two Cases
Follicular lymphoma is the most common form of low-grade B cell lymphoma. Follicular lymphoma occurs predominantly at lymph node sites and rarely in the gastrointestinal tract. Rare gastrointestinal follicular lymphoma is most commonly found in the small intestine, especially in the duodenum, and ap...
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Korean College of Helicobacter and Upper Gastrointestinal Research
2018-12-01
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| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
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| Online Access: | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.4.258 |
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| author | Hyeong Jin Kim Cheol Woong Choi Su Bum Park Su Jin Kim |
| author_facet | Hyeong Jin Kim Cheol Woong Choi Su Bum Park Su Jin Kim |
| author_sort | Hyeong Jin Kim |
| collection | DOAJ |
| description | Follicular lymphoma is the most common form of low-grade B cell lymphoma. Follicular lymphoma occurs predominantly at lymph node sites and rarely in the gastrointestinal tract. Rare gastrointestinal follicular lymphoma is most commonly found in the small intestine, especially in the duodenum, and appears as multiple granules. However, gastric follicular lymphoma mostly appears as a subepithelial tumor. We observed two primary gastric follicular lymphomas that resembled subepithelial tumors located in the body of the stomach. Endoscopic ultrasound revealed hypoechoic lesions located in the submucosa layer. Since endoscopic forceps biopsies were inconclusive, we performed endoscopic submucosal dissection, which resulted in a final pathologic diagnosis of follicular lymphoma. Because of the indolent nature of gastrointestinal follicular lymphoma, the “watch and wait” strategy can be applied in the early phase. The identification of endoscopic characteristics of gastric follicular lymphoma can be helpful for differential diagnosis and decision of treatment strategy. Therefore, we report two cases of primary gastrointestinal follicular lymphoma diagnosed following endoscopic submucosal dissection. |
| format | Article |
| id | doaj-art-16a4c9082a1048e2b6419e7fc0ae4645 |
| institution | Kabale University |
| issn | 1738-3331 |
| language | English |
| publishDate | 2018-12-01 |
| publisher | Korean College of Helicobacter and Upper Gastrointestinal Research |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj-art-16a4c9082a1048e2b6419e7fc0ae46452025-08-20T03:31:01ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312018-12-0118425826310.7704/kjhugr.2018.18.4.258kjhugr.2018.18.4.258Gastric Follicular Lymphomas Presenting as Subepithelial Tumors: Two CasesHyeong Jin Kim0Cheol Woong Choi1Su Bum Park2Su Jin Kim3Department of Internal Medicine, Pusan National University School of Medicine, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaFollicular lymphoma is the most common form of low-grade B cell lymphoma. Follicular lymphoma occurs predominantly at lymph node sites and rarely in the gastrointestinal tract. Rare gastrointestinal follicular lymphoma is most commonly found in the small intestine, especially in the duodenum, and appears as multiple granules. However, gastric follicular lymphoma mostly appears as a subepithelial tumor. We observed two primary gastric follicular lymphomas that resembled subepithelial tumors located in the body of the stomach. Endoscopic ultrasound revealed hypoechoic lesions located in the submucosa layer. Since endoscopic forceps biopsies were inconclusive, we performed endoscopic submucosal dissection, which resulted in a final pathologic diagnosis of follicular lymphoma. Because of the indolent nature of gastrointestinal follicular lymphoma, the “watch and wait” strategy can be applied in the early phase. The identification of endoscopic characteristics of gastric follicular lymphoma can be helpful for differential diagnosis and decision of treatment strategy. Therefore, we report two cases of primary gastrointestinal follicular lymphoma diagnosed following endoscopic submucosal dissection.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.4.258Endoscopic mucosal resectionFollicular lymphomaNeoplasms |
| spellingShingle | Hyeong Jin Kim Cheol Woong Choi Su Bum Park Su Jin Kim Gastric Follicular Lymphomas Presenting as Subepithelial Tumors: Two Cases The Korean Journal of Helicobacter and Upper Gastrointestinal Research Endoscopic mucosal resection Follicular lymphoma Neoplasms |
| title | Gastric Follicular Lymphomas Presenting as Subepithelial Tumors: Two Cases |
| title_full | Gastric Follicular Lymphomas Presenting as Subepithelial Tumors: Two Cases |
| title_fullStr | Gastric Follicular Lymphomas Presenting as Subepithelial Tumors: Two Cases |
| title_full_unstemmed | Gastric Follicular Lymphomas Presenting as Subepithelial Tumors: Two Cases |
| title_short | Gastric Follicular Lymphomas Presenting as Subepithelial Tumors: Two Cases |
| title_sort | gastric follicular lymphomas presenting as subepithelial tumors two cases |
| topic | Endoscopic mucosal resection Follicular lymphoma Neoplasms |
| url | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.4.258 |
| work_keys_str_mv | AT hyeongjinkim gastricfollicularlymphomaspresentingassubepithelialtumorstwocases AT cheolwoongchoi gastricfollicularlymphomaspresentingassubepithelialtumorstwocases AT subumpark gastricfollicularlymphomaspresentingassubepithelialtumorstwocases AT sujinkim gastricfollicularlymphomaspresentingassubepithelialtumorstwocases |