Colorectal cancer surgery in Serbia 2010-2014: An evaluation of a multicenter registry

Background/Aim. Surgical registries and databases are especially valuable in monitoring the performances in cancer treatment and detecting potential problems. For Serbian patients with colorectal cancer (CRC), data regarding the treatment received, the factors that may impact the outcome, and whethe...

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Main Authors: Nikolić Aleksandra, Krnjajić Mina, Marković Velimir, Barišić Goran, Dimitrijević Ivan, Krivokapić Zoran
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2021-01-01
Series:Vojnosanitetski Pregled
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Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900080N.pdf
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author Nikolić Aleksandra
Krnjajić Mina
Marković Velimir
Barišić Goran
Dimitrijević Ivan
Krivokapić Zoran
author_facet Nikolić Aleksandra
Krnjajić Mina
Marković Velimir
Barišić Goran
Dimitrijević Ivan
Krivokapić Zoran
author_sort Nikolić Aleksandra
collection DOAJ
description Background/Aim. Surgical registries and databases are especially valuable in monitoring the performances in cancer treatment and detecting potential problems. For Serbian patients with colorectal cancer (CRC), data regarding the treatment received, the factors that may impact the outcome, and whether or not treatment is successful and appropriate are not currently captured. The aim of this study was to establish a collection of a consensus dataset capturing surgical treatment of CRC at multiple public hospitals across Serbia and estimate outcome in CRC patients subjected to surgical treatment in the period 2010–2014. Methods. The study encompassed all 52 public CRC surgical units in Serbia. Numerical data on all patients who underwent operative CRC resection were included. An electronic database was created and overseen by the First Surgical Clinic of the Clinical Center of Serbia, Belgrade. Data were collected independently using a specifically designed standardized questionnaire, including the number of operated patients, localization of the primary tumor, type of surgical intervention, type and urgency of surgical intervention, and postoperative mortality. Results. A total number of 22,037 colorectal surgical procedures was performed in Serbia in the period 2010–2014 (approximately 4,400 per year). It was shown that 78.5% of the total number of procedures were elective and 21.5% were emergency. The most common cause of emergency surgeries was ileus (3,618 cases, 76.4%), while the less common causes were perforation (899 cases, 18.9%) and bleeding (216 cases, 4.5%). Postoperative mortality during the study period expressed as a percentage of all interventions for CRC was 2.8% on average with a slight increasing tendency. At the end of the study period, 127 doctors were educated for performing colonoscopy. Conclusion. The main outcome of this study was the establishment of the necessary preconditions for the multicenter data collection involving large numbers of CRC patients. The study supported the premise that the development of the national database for surgical treatment of CRC is achievable and could provide valuable insight into the routine surgical management of CRC in Serbia, creating a significant resource for further research.
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spelling doaj-art-16a37ac9f2774c8097b6dbc0fee5a3212025-08-20T03:54:32ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202021-01-0178444044410.2298/VSP190610080N0042-84501900080NColorectal cancer surgery in Serbia 2010-2014: An evaluation of a multicenter registryNikolić Aleksandra0https://orcid.org/0000-0003-3420-3896Krnjajić Mina1Marković Velimir2Barišić Goran3Dimitrijević Ivan4Krivokapić Zoran5https://orcid.org/0000-0002-5405-7366University of Belgrade, Institute of Molecular Genetics and Genetic Engineering, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + Clinical Center of Serbia, First Surgical Clinic, Department of Colorectal Surgery, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + Clinical Center of Serbia, First Surgical Clinic, Department of Colorectal Surgery, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + Clinical Center of Serbia, First Surgical Clinic, Department of Colorectal Surgery, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + Clinical Center of Serbia, First Surgical Clinic, Department of Colorectal Surgery, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + Clinical Center of Serbia, First Surgical Clinic, Department of Colorectal Surgery, Belgrade, SerbiaBackground/Aim. Surgical registries and databases are especially valuable in monitoring the performances in cancer treatment and detecting potential problems. For Serbian patients with colorectal cancer (CRC), data regarding the treatment received, the factors that may impact the outcome, and whether or not treatment is successful and appropriate are not currently captured. The aim of this study was to establish a collection of a consensus dataset capturing surgical treatment of CRC at multiple public hospitals across Serbia and estimate outcome in CRC patients subjected to surgical treatment in the period 2010–2014. Methods. The study encompassed all 52 public CRC surgical units in Serbia. Numerical data on all patients who underwent operative CRC resection were included. An electronic database was created and overseen by the First Surgical Clinic of the Clinical Center of Serbia, Belgrade. Data were collected independently using a specifically designed standardized questionnaire, including the number of operated patients, localization of the primary tumor, type of surgical intervention, type and urgency of surgical intervention, and postoperative mortality. Results. A total number of 22,037 colorectal surgical procedures was performed in Serbia in the period 2010–2014 (approximately 4,400 per year). It was shown that 78.5% of the total number of procedures were elective and 21.5% were emergency. The most common cause of emergency surgeries was ileus (3,618 cases, 76.4%), while the less common causes were perforation (899 cases, 18.9%) and bleeding (216 cases, 4.5%). Postoperative mortality during the study period expressed as a percentage of all interventions for CRC was 2.8% on average with a slight increasing tendency. At the end of the study period, 127 doctors were educated for performing colonoscopy. Conclusion. The main outcome of this study was the establishment of the necessary preconditions for the multicenter data collection involving large numbers of CRC patients. The study supported the premise that the development of the national database for surgical treatment of CRC is achievable and could provide valuable insight into the routine surgical management of CRC in Serbia, creating a significant resource for further research.http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900080N.pdfcolorectal neoplasmsdatabase as topicgeneral surgerymortalityserbiasurgical procedures, operativesurveys and questionnaires
spellingShingle Nikolić Aleksandra
Krnjajić Mina
Marković Velimir
Barišić Goran
Dimitrijević Ivan
Krivokapić Zoran
Colorectal cancer surgery in Serbia 2010-2014: An evaluation of a multicenter registry
Vojnosanitetski Pregled
colorectal neoplasms
database as topic
general surgery
mortality
serbia
surgical procedures, operative
surveys and questionnaires
title Colorectal cancer surgery in Serbia 2010-2014: An evaluation of a multicenter registry
title_full Colorectal cancer surgery in Serbia 2010-2014: An evaluation of a multicenter registry
title_fullStr Colorectal cancer surgery in Serbia 2010-2014: An evaluation of a multicenter registry
title_full_unstemmed Colorectal cancer surgery in Serbia 2010-2014: An evaluation of a multicenter registry
title_short Colorectal cancer surgery in Serbia 2010-2014: An evaluation of a multicenter registry
title_sort colorectal cancer surgery in serbia 2010 2014 an evaluation of a multicenter registry
topic colorectal neoplasms
database as topic
general surgery
mortality
serbia
surgical procedures, operative
surveys and questionnaires
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84501900080N.pdf
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AT krnjajicmina colorectalcancersurgeryinserbia20102014anevaluationofamulticenterregistry
AT markovicvelimir colorectalcancersurgeryinserbia20102014anevaluationofamulticenterregistry
AT barisicgoran colorectalcancersurgeryinserbia20102014anevaluationofamulticenterregistry
AT dimitrijevicivan colorectalcancersurgeryinserbia20102014anevaluationofamulticenterregistry
AT krivokapiczoran colorectalcancersurgeryinserbia20102014anevaluationofamulticenterregistry