Characterization of Aedes aegypti innate-immune pathways that limit Chikungunya virus replication.

Characterization of Aedes aegypti innate-immune pathways that limit Chikungunya virus replication.

Replication of arboviruses in their arthropod vectors is controlled by innate immune responses. The RNA sequence-specific break down mechanism, RNA interference (RNAi), has been shown to be an important innate antiviral response in mosquitoes. In addition, immune signaling pathways have been reporte...

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Main Authors: Melanie McFarlane, Camilo Arias-Goeta, Estelle Martin, Zoe O'Hara, Aleksei Lulla, Laurence Mousson, Stephanie M Rainey, Suzana Misbah, Esther Schnettler, Claire L Donald, Andres Merits, Alain Kohl, Anna-Bella Failloux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0002994
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