Inhibition of USP22 by miR-200b-5p represses gastric cancer cell proliferation and migration by targeting the NF-κB signaling pathway

Inhibition of USP22 by miR-200b-5p represses gastric cancer cell proliferation and migration by targeting the NF-κB signaling pathway

Gastric cancer (GC) is an aggressive tumor type with an intricate pathogenesis and limited therapeutic options. Ubiquitin-specific protease 22 (USP22) is a protein implicated in cell proliferation, metastasis, and tumorigenesis. However, the regulatory mechanisms governing USP22 in GC are still not...

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Bibliographic Details
Main Authors: Guo Yingying, Zhang Panpan, Gao Zhixing, Liu Xiaotian, Su Chen, Chen Su, An Tao, Hou Jingjing
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-12-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
USP22
miR-200b-5p
NF-κB
gastric neoplasm
cell proliferation
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024231
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