Correlation of Occlusion Asymmetry and Temporomandibular Disorders: A Cross-Sectional Study

Background: The association between occlusion and temporomandibular disorders (TMD) remains obscure. The present purpose was to explore the asymmetrical occlusion feature(s) potentially linked to TMDs. Methods: This study enrolled 148 patients with a chief complaint of malocclusion. Of those, 84 had...

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Main Authors: Donghui Guo, Jie Gao, Wen Qin, Xian Wang, Shaoxiong Guo, Zuolin Jin, Meiqing Wang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:International Dental Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S0020653925000115
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author Donghui Guo
Jie Gao
Wen Qin
Xian Wang
Shaoxiong Guo
Zuolin Jin
Meiqing Wang
author_facet Donghui Guo
Jie Gao
Wen Qin
Xian Wang
Shaoxiong Guo
Zuolin Jin
Meiqing Wang
author_sort Donghui Guo
collection DOAJ
description Background: The association between occlusion and temporomandibular disorders (TMD) remains obscure. The present purpose was to explore the asymmetrical occlusion feature(s) potentially linked to TMDs. Methods: This study enrolled 148 patients with a chief complaint of malocclusion. Of those, 84 had no signs of TMD (Group-ORD1), and 64 had signs of TMD (Group-ORD2). An additional 84 patients with a chief complaint of TMD symptoms and a history of orthodontic therapy were included (Group-TMD). All patients in the study were female. Asymmetry of six occlusion variables was measured on plaster study casts and recorded as 1 for asymmetry and 0 for symmetry. The variables contain the sagittal asymmetry: the first molar mesial-distal relationship (F1), canine mesial-distal relationship (F2); the horizontal asymmetry: anterior overjet and overbite relationship (F3), posterior overjet and overbite relationship (F4); missing teeth (F5), and the weight of the asymmetrical occluding pair (F6). And logistic regression model was used for data analyses. Results: In the analyses for Group-ORD2 versus Group-ORD1, the F6 variable and the interactions of F1*F2 and F1*F2*F6 were entered into the model (all OR > 2.68). For Group-TMD versus Group-ORD1, the variables were F1, F5, and F6 (all OR > 2.39) and F4 (OR = 0.28), and the interactions were F5*F6, F1*F2*F6, F1*F5*F6, and F1*F2*F5*F6 (all OR > 2.78) and F2*F4, F3*F5, and F2*F4*F6 (all OR < 0.13). For Group-TMD versus Group-ORD2 the variables and interactions were F5, F5*F6, and F1*F5*F6 (all OR > 4.03) and F4, F4*F6 and F2*F4*F6 (all OR < 0.21) (all P < .05). Conclusions: Patients with sagittal asymmetry, asymmetrical missing teeth, or asymmetrical weight of contact have a higher prevalence of TMD.
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spelling doaj-art-168b9813bddf4213af70ede6ebdb37972025-08-20T03:09:12ZengElsevierInternational Dental Journal0020-65392025-06-017532053206110.1016/j.identj.2025.01.003Correlation of Occlusion Asymmetry and Temporomandibular Disorders: A Cross-Sectional StudyDonghui Guo0Jie Gao1Wen Qin2Xian Wang3Shaoxiong Guo4Zuolin Jin5Meiqing Wang6State Key Laboratory of Military Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, Fourth Military Medical University, Xi'an, ChinaState Key Laboratory of Military Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, Fourth Military Medical University, Xi'an, ChinaState Key Laboratory of Military Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, Fourth Military Medical University, Xi'an, ChinaState Key Laboratory of Military Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, Fourth Military Medical University, Xi'an, ChinaState Key Laboratory of Military Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; Shaanxi International Joint Research Center for Oral Diseases, Department of Oral Anatomy and Physiology and TMD, School of Stomatology, Fourth Military Medical University, Xi'an, ChinaState Key Laboratory of Military Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, Fourth Military Medical University, Xi'an, China; Corresponding authors. Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Scientific Research and Teaching Center, Shanghai Stomatological Hospital &amp; School of Stomatology, No. 2 Tianjin Road, Shanghai, China; Department of Orthodontics, School of Stomatology, Fourth Military Medical University, 145 West Changle Road, Xi'an, P.R. China, 710032.Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Shanghai Stomatological Hospital, Fudan University, Shanghai, China; State Key Laboratory of Military Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; Shaanxi International Joint Research Center for Oral Diseases, Department of Oral Anatomy and Physiology and TMD, School of Stomatology, Fourth Military Medical University, Xi'an, China; Corresponding authors. Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Scientific Research and Teaching Center, Shanghai Stomatological Hospital &amp; School of Stomatology, No. 2 Tianjin Road, Shanghai, China; Department of Orthodontics, School of Stomatology, Fourth Military Medical University, 145 West Changle Road, Xi'an, P.R. China, 710032.Background: The association between occlusion and temporomandibular disorders (TMD) remains obscure. The present purpose was to explore the asymmetrical occlusion feature(s) potentially linked to TMDs. Methods: This study enrolled 148 patients with a chief complaint of malocclusion. Of those, 84 had no signs of TMD (Group-ORD1), and 64 had signs of TMD (Group-ORD2). An additional 84 patients with a chief complaint of TMD symptoms and a history of orthodontic therapy were included (Group-TMD). All patients in the study were female. Asymmetry of six occlusion variables was measured on plaster study casts and recorded as 1 for asymmetry and 0 for symmetry. The variables contain the sagittal asymmetry: the first molar mesial-distal relationship (F1), canine mesial-distal relationship (F2); the horizontal asymmetry: anterior overjet and overbite relationship (F3), posterior overjet and overbite relationship (F4); missing teeth (F5), and the weight of the asymmetrical occluding pair (F6). And logistic regression model was used for data analyses. Results: In the analyses for Group-ORD2 versus Group-ORD1, the F6 variable and the interactions of F1*F2 and F1*F2*F6 were entered into the model (all OR > 2.68). For Group-TMD versus Group-ORD1, the variables were F1, F5, and F6 (all OR > 2.39) and F4 (OR = 0.28), and the interactions were F5*F6, F1*F2*F6, F1*F5*F6, and F1*F2*F5*F6 (all OR > 2.78) and F2*F4, F3*F5, and F2*F4*F6 (all OR < 0.13). For Group-TMD versus Group-ORD2 the variables and interactions were F5, F5*F6, and F1*F5*F6 (all OR > 4.03) and F4, F4*F6 and F2*F4*F6 (all OR < 0.21) (all P < .05). Conclusions: Patients with sagittal asymmetry, asymmetrical missing teeth, or asymmetrical weight of contact have a higher prevalence of TMD.http://www.sciencedirect.com/science/article/pii/S0020653925000115Logistic modelsorthodonticstemporomandibular joint disorders
spellingShingle Donghui Guo
Jie Gao
Wen Qin
Xian Wang
Shaoxiong Guo
Zuolin Jin
Meiqing Wang
Correlation of Occlusion Asymmetry and Temporomandibular Disorders: A Cross-Sectional Study
International Dental Journal
Logistic models
orthodontics
temporomandibular joint disorders
title Correlation of Occlusion Asymmetry and Temporomandibular Disorders: A Cross-Sectional Study
title_full Correlation of Occlusion Asymmetry and Temporomandibular Disorders: A Cross-Sectional Study
title_fullStr Correlation of Occlusion Asymmetry and Temporomandibular Disorders: A Cross-Sectional Study
title_full_unstemmed Correlation of Occlusion Asymmetry and Temporomandibular Disorders: A Cross-Sectional Study
title_short Correlation of Occlusion Asymmetry and Temporomandibular Disorders: A Cross-Sectional Study
title_sort correlation of occlusion asymmetry and temporomandibular disorders a cross sectional study
topic Logistic models
orthodontics
temporomandibular joint disorders
url http://www.sciencedirect.com/science/article/pii/S0020653925000115
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