Function of manchette and intra-manchette transport in spermatogenesis and male fertility

Function of manchette and intra-manchette transport in spermatogenesis and male fertility

Abstract The manchette is a transient skirt-like structure consisting of microtubules (MTs) and filamentous actin (F-actin) surrounding the elongating sperm head during spermiogenesis. It is pivotal in sperm head shaping controlled by the acrosome-acroplaxome-manchette complex, acrosome formation, a...

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Bibliographic Details
Main Authors: Tingting Gao, Yang Liu, Jie Li, Yvxia Zhang, Bin Wu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cell Communication and Signaling
Subjects:
Manchette
IMT
Spermatogenesis
Infertility
AAM axis
LINC complex
Online Access:https://doi.org/10.1186/s12964-025-02213-z
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