Genomic Deletion of PfHRP2 and PfHRP3 in Plasmodium falciparum Strains, Ethiopia, 2009

Genomic Deletion of PfHRP2 and PfHRP3 in Plasmodium falciparum Strains, Ethiopia, 2009

Plasmodium falciparum strains lacking P. falciparum histidine-rich protein 2 (PfHRP2) and PfHRP3 threaten malaria rapid test reliability. We show that pfhrp2/pfhrp3–deleted parasites circulated in Ethiopia as early as 2009, before widespread PfHRP2-based rapid test use, and had high pfhrp3 deletion...

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Bibliographic Details
Main Authors: Tamirat Gebru Woldearegai, Tina Krüger, Sindew Mekasha Feleke, Hassen Mamo, Tesfaye Gelanew, Vanessa Krohmer, Sabine Belard, Peter G. Kremsner, Jana Held, Miriam Rodi, Andrea Kreidenweiss
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2025-07-01
Series:Emerging Infectious Diseases
Subjects:
malaria
parasites
Plasmodium falciparum
gene deletion
vector-borne infections
Ethiopia
Online Access:https://wwwnc.cdc.gov/eid/article/31/7/24-1676_article
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