Palmitoylation regulators drive the progression of clear cell renal cell carcinoma through Inhibition of cuproptosis: insights into the role of ZDHHC18

Palmitoylation regulators drive the progression of clear cell renal cell carcinoma through Inhibition of cuproptosis: insights into the role of ZDHHC18

Abstract Background Protein palmitoylation is a reversible post-translational modification that increases protein hydrophobicity, which can affect protein localization, stability, and function. Although palmitoylation is frequently observed in various cancers, the specific mechanisms by which it inf...

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Bibliographic Details
Main Authors: Wei Xu, Xiao-chao Chen, Yang Wang, Jian-chun Chen, Zhi-jun Cao, Ru Huang, Chao Chen, Dao-rong Hou, Min-jun Jiang, Chen Xu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cancer Cell International
Subjects:
Protein s-palmitoylation
CcRCC
ZDHHC18
Cuproptosis
Online Access:https://doi.org/10.1186/s12935-025-03882-z
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