Fractalkine/CX3CR1-Dependent Modulation of Synaptic and Network Plasticity in Health and Disease

CX3CR1 is a G protein-coupled receptor that is expressed exclusively by microglia within the brain parenchyma. The only known physiological CX3CR1 ligand is the chemokine fractalkine (FKN), which is constitutively expressed in neuronal cell membranes and tonically released by them. Through its key r...

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Bibliographic Details
Main Authors: N. P. Camacho-Hernández, F. Peña-Ortega
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2023/4637073
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