Chitosan oligosaccharide alleviates DON-induced liver injury via suppressing ferroptosis in mice

Chitosan oligosaccharide alleviates DON-induced liver injury via suppressing ferroptosis in mice

Chitosan oligosaccharide (COS), a water-soluble derivative of chitin, has been recognized for its diverse biological properties. Deoxynivalenol (DON) is a prevalent mycotoxin, causing extreme liver damage. However, the mechanism whereby COS alleviates DON-induced liver injury remains unclear. In the...

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Bibliographic Details
Main Authors: Mengjie Liu, Zhenlin Li, Jie Li, Guorong Yan, Chaoqi Liu, Qingqiang Yin, Yeqiang Liu, Xiaoxiang Xu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Chitosan oligosaccharide
Deoxynivalenol
Liver
Ferroptosis
Nrf2/HO-1/NF-κB
GPX4
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324016063
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