Ulnar sensory-motor amplitude ratio: a new tool to differentiate ganglionopathy from polyneuropathy
The objective of this study was to evaluate if the ratio of ulnar sensory nerve action potential (SNAP) over compound muscle action potential (CMAP) amplitudes (USMAR) would help in the distinction between ganglionopathy (GNP) and polyneuropathy (PNP). Methods We reviewed the nerve conductions stud...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações
2013-07-01
|
| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000700465&lng=en&tlng=en |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849703394603696128 |
|---|---|
| author | Raphael Ubirajara Garcia Joao Adilson Gama Ricardo Cassiana Abreu Horta Solange Garcia Garibaldi Anamarli Nucci Marcondes Cavalcante Franca Junior |
| author_facet | Raphael Ubirajara Garcia Joao Adilson Gama Ricardo Cassiana Abreu Horta Solange Garcia Garibaldi Anamarli Nucci Marcondes Cavalcante Franca Junior |
| author_sort | Raphael Ubirajara Garcia |
| collection | DOAJ |
| description | The objective of this study was to evaluate if the ratio of ulnar sensory nerve action potential (SNAP) over compound muscle action potential (CMAP) amplitudes (USMAR) would help in the distinction between ganglionopathy (GNP) and polyneuropathy (PNP). Methods We reviewed the nerve conductions studies and electromyography (EMG) of 18 GNP patients, 33 diabetic PNP patients and 56 controls. GNP was defined by simultaneous nerve conduction studies (NCS) and magnetic resonance imaging (MRI) abnormalities. PNP was defined by usual clinical and NCS criteria. We used ANOVA with post-hoc Tukey test and ROC curve analysis to compare ulnar SNAP and CMAP, as well as USMAR in the groups. Results Ulnar CMAP amplitudes were similar between GNP x PNP x Controls (p=0.253), but ulnar SNAP amplitudes (1.6±3.2 x 11.9±9.1 × 45.7±24.7) and USMAR values (0.3±0.3 × 1.5±0.9 × 4.6±2.2) were significantly different. A USMAR threshold of 0.71 was able to differentiate GNP and PNP (94.4% sensitivity and 90.9% specificity). Conclusions USMAR is a practical and reliable tool for the differentiation between GNP and PNP. |
| format | Article |
| id | doaj-art-1664c1997373447b88fcb893b4e9da25 |
| institution | DOAJ |
| issn | 1678-4227 |
| language | English |
| publishDate | 2013-07-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-1664c1997373447b88fcb893b4e9da252025-08-20T03:17:18ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272013-07-0171746546910.1590/0004-282X20130063S0004-282X2013000700465Ulnar sensory-motor amplitude ratio: a new tool to differentiate ganglionopathy from polyneuropathyRaphael Ubirajara GarciaJoao Adilson Gama RicardoCassiana Abreu HortaSolange Garcia GaribaldiAnamarli NucciMarcondes Cavalcante Franca JuniorThe objective of this study was to evaluate if the ratio of ulnar sensory nerve action potential (SNAP) over compound muscle action potential (CMAP) amplitudes (USMAR) would help in the distinction between ganglionopathy (GNP) and polyneuropathy (PNP). Methods We reviewed the nerve conductions studies and electromyography (EMG) of 18 GNP patients, 33 diabetic PNP patients and 56 controls. GNP was defined by simultaneous nerve conduction studies (NCS) and magnetic resonance imaging (MRI) abnormalities. PNP was defined by usual clinical and NCS criteria. We used ANOVA with post-hoc Tukey test and ROC curve analysis to compare ulnar SNAP and CMAP, as well as USMAR in the groups. Results Ulnar CMAP amplitudes were similar between GNP x PNP x Controls (p=0.253), but ulnar SNAP amplitudes (1.6±3.2 x 11.9±9.1 × 45.7±24.7) and USMAR values (0.3±0.3 × 1.5±0.9 × 4.6±2.2) were significantly different. A USMAR threshold of 0.71 was able to differentiate GNP and PNP (94.4% sensitivity and 90.9% specificity). Conclusions USMAR is a practical and reliable tool for the differentiation between GNP and PNP.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000700465&lng=en&tlng=enneurofisiologia clinicaganglionopatiapolineuropatianeuronopatia sensitivanervo ulnar |
| spellingShingle | Raphael Ubirajara Garcia Joao Adilson Gama Ricardo Cassiana Abreu Horta Solange Garcia Garibaldi Anamarli Nucci Marcondes Cavalcante Franca Junior Ulnar sensory-motor amplitude ratio: a new tool to differentiate ganglionopathy from polyneuropathy Arquivos de Neuro-Psiquiatria neurofisiologia clinica ganglionopatia polineuropatia neuronopatia sensitiva nervo ulnar |
| title | Ulnar sensory-motor amplitude ratio: a new tool to differentiate ganglionopathy from polyneuropathy |
| title_full | Ulnar sensory-motor amplitude ratio: a new tool to differentiate ganglionopathy from polyneuropathy |
| title_fullStr | Ulnar sensory-motor amplitude ratio: a new tool to differentiate ganglionopathy from polyneuropathy |
| title_full_unstemmed | Ulnar sensory-motor amplitude ratio: a new tool to differentiate ganglionopathy from polyneuropathy |
| title_short | Ulnar sensory-motor amplitude ratio: a new tool to differentiate ganglionopathy from polyneuropathy |
| title_sort | ulnar sensory motor amplitude ratio a new tool to differentiate ganglionopathy from polyneuropathy |
| topic | neurofisiologia clinica ganglionopatia polineuropatia neuronopatia sensitiva nervo ulnar |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000700465&lng=en&tlng=en |
| work_keys_str_mv | AT raphaelubirajaragarcia ulnarsensorymotoramplituderatioanewtooltodifferentiateganglionopathyfrompolyneuropathy AT joaoadilsongamaricardo ulnarsensorymotoramplituderatioanewtooltodifferentiateganglionopathyfrompolyneuropathy AT cassianaabreuhorta ulnarsensorymotoramplituderatioanewtooltodifferentiateganglionopathyfrompolyneuropathy AT solangegarciagaribaldi ulnarsensorymotoramplituderatioanewtooltodifferentiateganglionopathyfrompolyneuropathy AT anamarlinucci ulnarsensorymotoramplituderatioanewtooltodifferentiateganglionopathyfrompolyneuropathy AT marcondescavalcantefrancajunior ulnarsensorymotoramplituderatioanewtooltodifferentiateganglionopathyfrompolyneuropathy |