Generic comparison of lumen nucleation and fusion in epithelial organoids with and without hydrostatic pressure

Generic comparison of lumen nucleation and fusion in epithelial organoids with and without hydrostatic pressure

Abstract Many internal organs in the body harbor a fluid-filled lumen. Lumen nucleation and fusion have been reported as dependent on organ-type during organogenesis. In contrast, the physics of lumen suggests that force balance between luminal pressure and cell mechanics leads to generic rules. How...

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Bibliographic Details
Main Authors: Linjie Lu, Kana Fuji, Tristan Guyomar, Michèle Lieb, Marie André, Sakurako Tanida, Makiko Nonomura, Tetsuya Hiraiwa, Yara Alcheikh, Siham Yennek, Heike Petzold, Cecilie Martin-Lemaitre, Anne Grapin-Botton, Alf Honigmann, Masaki Sano, Daniel Riveline
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60780-8
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