Generic comparison of lumen nucleation and fusion in epithelial organoids with and without hydrostatic pressure
Abstract Many internal organs in the body harbor a fluid-filled lumen. Lumen nucleation and fusion have been reported as dependent on organ-type during organogenesis. In contrast, the physics of lumen suggests that force balance between luminal pressure and cell mechanics leads to generic rules. How...
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| Main Authors: | Linjie Lu, Kana Fuji, Tristan Guyomar, Michèle Lieb, Marie André, Sakurako Tanida, Makiko Nonomura, Tetsuya Hiraiwa, Yara Alcheikh, Siham Yennek, Heike Petzold, Cecilie Martin-Lemaitre, Anne Grapin-Botton, Alf Honigmann, Masaki Sano, Daniel Riveline |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-60780-8 |
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