Integrating analysis of multi-omics summary data identifies novel plasma protein biomarkers and drug targets for bladder cancer

Integrating analysis of multi-omics summary data identifies novel plasma protein biomarkers and drug targets for bladder cancer

Abstract The plasma proteins are an important source of therapeutic targets. This study aims to address the diagnostic and therapeutic challenges of bladder cancer (BC) by using Mendelian randomization (MR) with a large sample size from multiple centers to identify the plasma proteins which are caus...

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Bibliographic Details
Main Authors: Jinlong Cao, Siyu Chen, Jirong Wang, Xinpeng Fan, Shanhui Liu, Jiaqi Shan, Xiaoran Li, Li Yang
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Mendelian randomization
Plasma proteins
Bladder cancer
Single-cell RNA-seq
Online Access:https://doi.org/10.1007/s12672-025-02476-5
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