Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses

**Background:** Studies have shown that improvements in glycemic control are associated with avoidance or delayed onset of diabetes complications, improvements in health-related quality of life, and reductions in diabetes-related health care costs. Clinical practice guidelines recommend maintaining...

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Main Authors: John E. Schneider, Anjani Parikh, Ivana Stojanovic
Format: Article
Language:English
Published: Columbia Data Analytics, LLC 2018-02-01
Series:Journal of Health Economics and Outcomes Research
Online Access:https://doi.org/10.36469/9783
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author John E. Schneider
Anjani Parikh
Ivana Stojanovic
author_facet John E. Schneider
Anjani Parikh
Ivana Stojanovic
author_sort John E. Schneider
collection DOAJ
description **Background:** Studies have shown that improvements in glycemic control are associated with avoidance or delayed onset of diabetes complications, improvements in health-related quality of life, and reductions in diabetes-related health care costs. Clinical practice guidelines recommend maintaining a hemoglobin A1c (HbA1c) level less than 7%, but among type 2 diabetes patients using insulin, two-thirds have HbA1c above 7% and one-third have HbA1c above 9%. **Objectives:** This study examined the use of insulin management services to enable patients to optimize insulin dosing to achieve HbA1c targets and subsequently reduce health care costs. Cost savings may be achieved through reduced complications and hospitalizations, as well as reduced outpatient, physician, and clinic costs. This study quantified the reduction in pharmaceutical expenses related to the use of an enhanced insulin management service to improve glycemic control. **Methods:** Two hundred seventeen insulin-reliant patients were enrolled in the d-Nav® Insulin Guidance Service through a participating insurance group. A prospective cost analysis was conducted using data from enrolled patients who completed the first 90 days of follow up. **Results:** Of the 192 patients who completed the 90-day study period, 54 (28.13%) were prescribed one or more expensive medications at baseline, but 45 (83.33%) of those patients were eligible for medication discontinuation after 90 days. At baseline, the annual cost of expensive medications per patient was $7564 (CI: $5191-$9938) and $1483 (CI: -$1463-$4429) at 90 days (p<0.001). Direct savings from medication elimination was estimated to be $145 per patient per month (PPPM) or $1736 per patient per year (PPPY) for all patients and $514 PPPM/$6172 PPPY for the target group. Patients that completed the 90-day period significantly reduced HbA1c levels from 9.37% (CI:7.72%-11.03%) at baseline to 7.71% (CI: 6.70%-8.73%) (p<0.001). A total of 170 (88.54%) patients had improved HbA1c at 90 days. **Conclusions:** Use of the insulin guidance service achieved improved glycemic control by optimizing insulin dosing, which enabled most patients using the service to reduce or eliminate the use of expensive diabetes medications. Further study is needed to assess the impact of optimized insulin dosing on other diabetes related health care costs in a usual practice setting.
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spelling doaj-art-16300b572f4445ecbb7f72ecfd5df7292025-02-10T16:13:14ZengColumbia Data Analytics, LLCJournal of Health Economics and Outcomes Research2327-22362018-02-0161Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical ExpensesJohn E. SchneiderAnjani ParikhIvana Stojanovic**Background:** Studies have shown that improvements in glycemic control are associated with avoidance or delayed onset of diabetes complications, improvements in health-related quality of life, and reductions in diabetes-related health care costs. Clinical practice guidelines recommend maintaining a hemoglobin A1c (HbA1c) level less than 7%, but among type 2 diabetes patients using insulin, two-thirds have HbA1c above 7% and one-third have HbA1c above 9%. **Objectives:** This study examined the use of insulin management services to enable patients to optimize insulin dosing to achieve HbA1c targets and subsequently reduce health care costs. Cost savings may be achieved through reduced complications and hospitalizations, as well as reduced outpatient, physician, and clinic costs. This study quantified the reduction in pharmaceutical expenses related to the use of an enhanced insulin management service to improve glycemic control. **Methods:** Two hundred seventeen insulin-reliant patients were enrolled in the d-Nav® Insulin Guidance Service through a participating insurance group. A prospective cost analysis was conducted using data from enrolled patients who completed the first 90 days of follow up. **Results:** Of the 192 patients who completed the 90-day study period, 54 (28.13%) were prescribed one or more expensive medications at baseline, but 45 (83.33%) of those patients were eligible for medication discontinuation after 90 days. At baseline, the annual cost of expensive medications per patient was $7564 (CI: $5191-$9938) and $1483 (CI: -$1463-$4429) at 90 days (p<0.001). Direct savings from medication elimination was estimated to be $145 per patient per month (PPPM) or $1736 per patient per year (PPPY) for all patients and $514 PPPM/$6172 PPPY for the target group. Patients that completed the 90-day period significantly reduced HbA1c levels from 9.37% (CI:7.72%-11.03%) at baseline to 7.71% (CI: 6.70%-8.73%) (p<0.001). A total of 170 (88.54%) patients had improved HbA1c at 90 days. **Conclusions:** Use of the insulin guidance service achieved improved glycemic control by optimizing insulin dosing, which enabled most patients using the service to reduce or eliminate the use of expensive diabetes medications. Further study is needed to assess the impact of optimized insulin dosing on other diabetes related health care costs in a usual practice setting.https://doi.org/10.36469/9783
spellingShingle John E. Schneider
Anjani Parikh
Ivana Stojanovic
Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses
Journal of Health Economics and Outcomes Research
title Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses
title_full Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses
title_fullStr Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses
title_full_unstemmed Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses
title_short Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses
title_sort impact of a novel insulin management service on non insulin pharmaceutical expenses
url https://doi.org/10.36469/9783
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