Human naïve B cells show evidence of anergy and clonal redemption following vaccination
Abstract In an era of predicted emerging pandemics, the production of effective vaccines may require an in-depth understanding of the biology of human naive B (BN) cells. Here we provide evidence that the majority of BN cells expressed CD73, an ecto-5’-nucleotidase often associated with immune cell...
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| Main Authors: | Brian L. P. Dizon, Prasida Holla, Evan C. Mutic, Paul Schaughency, Susan K. Pierce |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-025-01133-w |
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