Obesity Epidemic is an Introduction of Type 2 Diabetes Mellitus and Alzheimer\'s Epidemic

The global rise of obesity has increased the prevalence of type 2 diabetes mellitus (T2DM) and the risk of Alzheimer’s disease (AD). The obesity, a key risk factor of T2DM, leads to insulin resistance, which contributes to cognitive decline and potentially AD through shared metabolic pathways. This...

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Main Authors: Roya Rafaiee, Seyedeh Maryam Mousavi Bourkheili, Raheleh Rafaiee
Format: Article
Language:English
Published: Shahid Sadoughi University of Medical Sciences 2025-05-01
Series:Iranian Journal of Diabetes and Obesity
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Online Access:http://ijdo.ssu.ac.ir/article-1-949-en.pdf
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Summary:The global rise of obesity has increased the prevalence of type 2 diabetes mellitus (T2DM) and the risk of Alzheimer’s disease (AD). The obesity, a key risk factor of T2DM, leads to insulin resistance, which contributes to cognitive decline and potentially AD through shared metabolic pathways. This Commentary highlights the connection between obesity, T2DM, and AD, suggesting that lifestyle changes like weight loss and discontinuation of sugar consumption may help to prevent these conditions. Comprehensive public health strategies focusing on diet, exercise, and education are essential to reduce the growing health crisis and improve metabolic and cognitive health globally.
ISSN:2008-6792
2345-2250