Treatment of an Osteochondral Defect of the Trochlea Using Matrix-Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone Grafting
Chondral and osteochondral defects of the knee are painful and disabling in the short term, can lead to accelerated osteoarthritis in the long term, and have relatively poor healing potential. Although many cartilage restoration procedures exist for focal cartilage defects, matrix-induced autologous...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | Arthroscopy Techniques |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212628725000763 |
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| author | Rishi Trikha, M.D. Thomas J. Kremen, M.D. Paul J. Walker, M.D. Kristofer J. Jones, M.D. |
| author_facet | Rishi Trikha, M.D. Thomas J. Kremen, M.D. Paul J. Walker, M.D. Kristofer J. Jones, M.D. |
| author_sort | Rishi Trikha, M.D. |
| collection | DOAJ |
| description | Chondral and osteochondral defects of the knee are painful and disabling in the short term, can lead to accelerated osteoarthritis in the long term, and have relatively poor healing potential. Although many cartilage restoration procedures exist for focal cartilage defects, matrix-induced autologous chondrocyte implantation (MACI) for the appropriate patient has evolved as a reliable technique with encouraging long-term outcomes. Despite the reported favorable outcomes, there remains a relative dearth of literature on the use of MACI with autologous bone graft. This article presents a modified MACI sandwich technique that uses only 1 scaffold in combination with autologous bone graft from the proximal tibia to address an osteochondritis dissecans lesion of the lateral trochlea. This technique allows for both a stable MACI single-layer scaffold and a relatively efficient operative workflow. |
| format | Article |
| id | doaj-art-16258fd0dbae4495aa7f53ae7b58cf80 |
| institution | Kabale University |
| issn | 2212-6287 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Arthroscopy Techniques |
| spelling | doaj-art-16258fd0dbae4495aa7f53ae7b58cf802025-08-20T03:24:48ZengElsevierArthroscopy Techniques2212-62872025-06-0114610350710.1016/j.eats.2025.103507Treatment of an Osteochondral Defect of the Trochlea Using Matrix-Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone GraftingRishi Trikha, M.D.0Thomas J. Kremen, M.D.1Paul J. Walker, M.D.2Kristofer J. Jones, M.D.3Address correspondence to Rishi Trikha, M.D., Department of Orthopaedic Surgery, University of California, Los Angeles, 10833 Le Conte Ave, 76-143 CHS, Los Angeles, CA 90095, U.S.A.; Department of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, California, U.S.A.Department of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, California, U.S.A.Department of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, California, U.S.A.Department of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, California, U.S.A.Chondral and osteochondral defects of the knee are painful and disabling in the short term, can lead to accelerated osteoarthritis in the long term, and have relatively poor healing potential. Although many cartilage restoration procedures exist for focal cartilage defects, matrix-induced autologous chondrocyte implantation (MACI) for the appropriate patient has evolved as a reliable technique with encouraging long-term outcomes. Despite the reported favorable outcomes, there remains a relative dearth of literature on the use of MACI with autologous bone graft. This article presents a modified MACI sandwich technique that uses only 1 scaffold in combination with autologous bone graft from the proximal tibia to address an osteochondritis dissecans lesion of the lateral trochlea. This technique allows for both a stable MACI single-layer scaffold and a relatively efficient operative workflow.http://www.sciencedirect.com/science/article/pii/S2212628725000763 |
| spellingShingle | Rishi Trikha, M.D. Thomas J. Kremen, M.D. Paul J. Walker, M.D. Kristofer J. Jones, M.D. Treatment of an Osteochondral Defect of the Trochlea Using Matrix-Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone Grafting Arthroscopy Techniques |
| title | Treatment of an Osteochondral Defect of the Trochlea Using Matrix-Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone Grafting |
| title_full | Treatment of an Osteochondral Defect of the Trochlea Using Matrix-Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone Grafting |
| title_fullStr | Treatment of an Osteochondral Defect of the Trochlea Using Matrix-Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone Grafting |
| title_full_unstemmed | Treatment of an Osteochondral Defect of the Trochlea Using Matrix-Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone Grafting |
| title_short | Treatment of an Osteochondral Defect of the Trochlea Using Matrix-Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone Grafting |
| title_sort | treatment of an osteochondral defect of the trochlea using matrix induced autologous chondrocyte implantation and proximal tibia autologous bone grafting |
| url | http://www.sciencedirect.com/science/article/pii/S2212628725000763 |
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