Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome

High blood pressure is a significant risk factor for cardiovascular diseases and is linked to an increased risk of mild cognitive impairment (MCI). The lack of effective treatments for these conditions highlights the urgent need for novel therapeutic approaches. Recent research suggests that the gut...

Full description

Saved in:
Bibliographic Details
Main Authors: Xinlei Dong, Xiaomin Hao, Jian Wen, Qinfeng Yan, Kaixuan Ma, Qingguo Liu, Juan Li, Lili Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1495384/full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850244194966175744
author Xinlei Dong
Xinlei Dong
Xiaomin Hao
Jian Wen
Jian Wen
Qinfeng Yan
Qinfeng Yan
Kaixuan Ma
Kaixuan Ma
Qingguo Liu
Juan Li
Juan Li
Lili Zhang
Lili Zhang
author_facet Xinlei Dong
Xinlei Dong
Xiaomin Hao
Jian Wen
Jian Wen
Qinfeng Yan
Qinfeng Yan
Kaixuan Ma
Kaixuan Ma
Qingguo Liu
Juan Li
Juan Li
Lili Zhang
Lili Zhang
author_sort Xinlei Dong
collection DOAJ
description High blood pressure is a significant risk factor for cardiovascular diseases and is linked to an increased risk of mild cognitive impairment (MCI). The lack of effective treatments for these conditions highlights the urgent need for novel therapeutic approaches. Recent research suggests that the gut microbiota-brain-gut axis plays a crucial role in the pathogenesis of hypertension and MCI by regulating the nervous, endocrine, and immune systems. Acupuncture, an established therapeutic modality, has shown promise in influencing the course of hypertension and MCI by modulating the gut microbiota. This review aims to summarize the mechanistic relationships between the gut microbiome, hypertension, and MCI, and to explore the potential of acupuncture as a treatment strategy for managing Mild cognitive impairment in Hypertension concurrently.
format Article
id doaj-art-1622e2db98d84b97adbb59edc67d083a
institution OA Journals
issn 1662-453X
language English
publishDate 2024-12-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Neuroscience
spelling doaj-art-1622e2db98d84b97adbb59edc67d083a2025-08-20T01:59:48ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2024-12-011810.3389/fnins.2024.14953841495384Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiomeXinlei Dong0Xinlei Dong1Xiaomin Hao2Jian Wen3Jian Wen4Qinfeng Yan5Qinfeng Yan6Kaixuan Ma7Kaixuan Ma8Qingguo Liu9Juan Li10Juan Li11Lili Zhang12Lili Zhang13First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, ChinaFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaSchool of Acupuncture, Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaChengdu University of Traditional Chinese Medicine, College of Health Preservation and Rehabilitation, Chengdu, ChinaAffiliated Rehabilitation Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaHigh blood pressure is a significant risk factor for cardiovascular diseases and is linked to an increased risk of mild cognitive impairment (MCI). The lack of effective treatments for these conditions highlights the urgent need for novel therapeutic approaches. Recent research suggests that the gut microbiota-brain-gut axis plays a crucial role in the pathogenesis of hypertension and MCI by regulating the nervous, endocrine, and immune systems. Acupuncture, an established therapeutic modality, has shown promise in influencing the course of hypertension and MCI by modulating the gut microbiota. This review aims to summarize the mechanistic relationships between the gut microbiome, hypertension, and MCI, and to explore the potential of acupuncture as a treatment strategy for managing Mild cognitive impairment in Hypertension concurrently.https://www.frontiersin.org/articles/10.3389/fnins.2024.1495384/fullacupuncturegut microbiota-brain-gut axishypertensionmild cognitive impairmentintestinal flora
spellingShingle Xinlei Dong
Xinlei Dong
Xiaomin Hao
Jian Wen
Jian Wen
Qinfeng Yan
Qinfeng Yan
Kaixuan Ma
Kaixuan Ma
Qingguo Liu
Juan Li
Juan Li
Lili Zhang
Lili Zhang
Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome
Frontiers in Neuroscience
acupuncture
gut microbiota-brain-gut axis
hypertension
mild cognitive impairment
intestinal flora
title Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome
title_full Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome
title_fullStr Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome
title_full_unstemmed Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome
title_short Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome
title_sort study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome
topic acupuncture
gut microbiota-brain-gut axis
hypertension
mild cognitive impairment
intestinal flora
url https://www.frontiersin.org/articles/10.3389/fnins.2024.1495384/full
work_keys_str_mv AT xinleidong studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT xinleidong studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT xiaominhao studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT jianwen studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT jianwen studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT qinfengyan studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT qinfengyan studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT kaixuanma studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT kaixuanma studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT qingguoliu studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT juanli studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT juanli studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT lilizhang studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome
AT lilizhang studyonthemechanismofacupuncturetoimprovemildcognitiveimpairmentinhypertensionbyregulatingintestinalmicrobiome