Redox signaling modulates axonal microtubule organization and induces a specific phosphorylation signature of microtubule-regulating proteins

Redox signaling modulates axonal microtubule organization and induces a specific phosphorylation signature of microtubule-regulating proteins

Many life processes are regulated by physiological redox signaling, but excessive oxidative stress can damage biomolecules and contribute to disease. Neuronal microtubules are critically involved in axon homeostasis, regulation of axonal transport, and neurodegenerative processes. However, whether a...

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Bibliographic Details
Main Authors: Christian Conze, Nataliya I. Trushina, Nanci Monteiro-Abreu, Lisha Singh, Daniel Villar Romero, Eike Wienbeuker, Anna-Sophie Schwarze, Michael Holtmannspötter, Lidia Bakota, Roland Brandt
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Redox Biology
Subjects:
Microtubules
Tau
Axon
Redox signalling
Hydrogen peroxide
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725001399
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