Impaired Meningeal Lymphatic Drainage Aggravates LPS-Induced Neuroinflammation and Depression-Like Behaviors in Mice
Conclusion: The drainage function of mLVs is pivotal in inflammation of the CNS. Enhancing meningeal lymphatic improves the development of neuroinflammation and inflammation-induced depression-like behaviors. VEGFR3 could serve as a potential therapeutic target for CNS inflammation.
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/mi/4288671 |
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