Imaging and histopathological considerations in determining the primary site and differential diagnosis of gallbladder liposarcoma
Abstract This study aimed to address the article by Yang et al., titled “Primary giant liposarcoma of the gallbladder: A case report and literature review.” The authors reported an extremely rare case of a large atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) arising in the gallb...
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| Format: | Article |
| Language: | English |
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BMC
2025-07-01
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| Series: | World Journal of Surgical Oncology |
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| Online Access: | https://doi.org/10.1186/s12957-025-03915-x |
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| author | Jiro Ichikawa Shinji Furuya Tomonori Kawasaki Kojiro Onohara Masanori Wako Satoshi Ochiai Tetsuo Hagino Hirotaka Haro |
| author_facet | Jiro Ichikawa Shinji Furuya Tomonori Kawasaki Kojiro Onohara Masanori Wako Satoshi Ochiai Tetsuo Hagino Hirotaka Haro |
| author_sort | Jiro Ichikawa |
| collection | DOAJ |
| description | Abstract This study aimed to address the article by Yang et al., titled “Primary giant liposarcoma of the gallbladder: A case report and literature review.” The authors reported an extremely rare case of a large atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) arising in the gallbladder, diagnosed through imaging and histopathological findings. However, due to the tumor’s exceptional size, the positional relationship between the gallbladder and the tumor remains unclear. In such cases, it is essential to histologically analyze the interface between the tumor and the gallbladder. Additionally, imaging revealed both fatty and non-fatty components, necessitating consideration of dedifferentiated liposarcoma as a differential diagnosis. In light of these factors, this study discusses the specific information required for further evaluation and accurate diagnosis. |
| format | Article |
| id | doaj-art-160fe448dd2c42e8aac03dd18c5f2b43 |
| institution | Kabale University |
| issn | 1477-7819 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj-art-160fe448dd2c42e8aac03dd18c5f2b432025-08-20T03:45:35ZengBMCWorld Journal of Surgical Oncology1477-78192025-07-012311410.1186/s12957-025-03915-xImaging and histopathological considerations in determining the primary site and differential diagnosis of gallbladder liposarcomaJiro Ichikawa0Shinji Furuya1Tomonori Kawasaki2Kojiro Onohara3Masanori Wako4Satoshi Ochiai5Tetsuo Hagino6Hirotaka Haro7Department of Orthopedic Surgery, Interdisciplinary Graduate School of Medicine, University of YamanashiFirst Department of Surgery, Interdisciplinary Graduate School of Medicine, University of YamanashiDepartment of Pathology, Saitama Medical University International Medical CenterDepartment of Radiology, Interdisciplinary Graduate School of Medicine, University of YamanashiDepartment of Radiology, Interdisciplinary Graduate School of Medicine, University of YamanashiDepartment of Orthopedic Surgery, National Hospital Organization (NHO), Kofu National HospitalDepartment of Orthopedic Surgery, National Hospital Organization (NHO), Kofu National HospitalDepartment of Orthopedic Surgery, Interdisciplinary Graduate School of Medicine, University of YamanashiAbstract This study aimed to address the article by Yang et al., titled “Primary giant liposarcoma of the gallbladder: A case report and literature review.” The authors reported an extremely rare case of a large atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) arising in the gallbladder, diagnosed through imaging and histopathological findings. However, due to the tumor’s exceptional size, the positional relationship between the gallbladder and the tumor remains unclear. In such cases, it is essential to histologically analyze the interface between the tumor and the gallbladder. Additionally, imaging revealed both fatty and non-fatty components, necessitating consideration of dedifferentiated liposarcoma as a differential diagnosis. In light of these factors, this study discusses the specific information required for further evaluation and accurate diagnosis.https://doi.org/10.1186/s12957-025-03915-xWell-differentiated liposarcomaDedifferentiated liposarcomaImagingHistopathological findingsDifferential diagnosisPrimary site |
| spellingShingle | Jiro Ichikawa Shinji Furuya Tomonori Kawasaki Kojiro Onohara Masanori Wako Satoshi Ochiai Tetsuo Hagino Hirotaka Haro Imaging and histopathological considerations in determining the primary site and differential diagnosis of gallbladder liposarcoma World Journal of Surgical Oncology Well-differentiated liposarcoma Dedifferentiated liposarcoma Imaging Histopathological findings Differential diagnosis Primary site |
| title | Imaging and histopathological considerations in determining the primary site and differential diagnosis of gallbladder liposarcoma |
| title_full | Imaging and histopathological considerations in determining the primary site and differential diagnosis of gallbladder liposarcoma |
| title_fullStr | Imaging and histopathological considerations in determining the primary site and differential diagnosis of gallbladder liposarcoma |
| title_full_unstemmed | Imaging and histopathological considerations in determining the primary site and differential diagnosis of gallbladder liposarcoma |
| title_short | Imaging and histopathological considerations in determining the primary site and differential diagnosis of gallbladder liposarcoma |
| title_sort | imaging and histopathological considerations in determining the primary site and differential diagnosis of gallbladder liposarcoma |
| topic | Well-differentiated liposarcoma Dedifferentiated liposarcoma Imaging Histopathological findings Differential diagnosis Primary site |
| url | https://doi.org/10.1186/s12957-025-03915-x |
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