In vitro and in vivo evaluation of the leishmanicidal and cytotoxic activities of chitosan and chitosan–amphotericin B

In vitro and in vivo evaluation of the leishmanicidal and cytotoxic activities of chitosan and chitosan–amphotericin B

Abstract Cutaneous leishmaniasis (CL), classified as a neglected tropical disease (NTD), is a significant public health concern caused by Leishmania protozoa. It is transmitted through the bites of infected female sandflies and manifests in various forms, ranging from localized skin ulcers to social...

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Main Authors: Parisa Mousavi, Bahman Rahimi Esboei, Maryam Pourhajibagher, Azadeh Zolfaghari, Zabihollah Shahmoradi, Fatemeh Namdar, Somayyeh Ahmadi, Seyed Mahmood Mousavi, Fatemeh Parandin, Seyed Hossein Hejazi
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:AMB Express
Subjects:
Anti-leishmanial
Leishmania major
Cytotoxicity
Chitosan
Amphotericin B
Online Access:https://doi.org/10.1186/s13568-025-01877-7
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