Programmed Death Ligand 2 in Cancer-Induced Immune Suppression
Inhibitory molecules of the B7/CD28 family play a key role in the induction of immune tolerance in the tumor microenvironment. The programmed death-1 receptor (PD-1), with its ligands PD-L1 and PD-L2, constitutes an important member of these inhibitory pathways. The relevance of the PD-1/PD-L1 pathw...
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| Main Authors: | Esdy N. Rozali, Stanleyson V. Hato, Bruce W. Robinson, Richard A. Lake, W. Joost Lesterhuis |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Clinical and Developmental Immunology |
| Online Access: | http://dx.doi.org/10.1155/2012/656340 |
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