Severe Neuropsychiatric Reaction in a Deployed Military Member after Prophylactic Mefloquine

Recent studies of military personnel who have deployed to Iraq and Afghanistan have reported a number of combat-related psychiatric disorders such as posttraumatic stress disorder, depression, and traumatic brain injury. This case report involves a 27-year-old male active-duty US military service me...

Full description

Saved in:
Bibliographic Details
Main Authors: Alan L. Peterson, Robert A. Seegmiller, Libby S. Schindler
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2011/350417
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849308697803620352
author Alan L. Peterson
Robert A. Seegmiller
Libby S. Schindler
author_facet Alan L. Peterson
Robert A. Seegmiller
Libby S. Schindler
author_sort Alan L. Peterson
collection DOAJ
description Recent studies of military personnel who have deployed to Iraq and Afghanistan have reported a number of combat-related psychiatric disorders such as posttraumatic stress disorder, depression, and traumatic brain injury. This case report involves a 27-year-old male active-duty US military service member who developed severe depression, psychotic hallucinations, and neuropsychological sequelae following the prophylactic use of the antimalarial medication mefloquine hydrochloride. The patient had a recent history of depression and was taking antidepressant medications at the time of his deployment to the Middle East. Psychiatrists and other health care providers should be aware of the possible neuropsychiatric side effects of mefloquine in deployed military personnel and should consider the use of other medications for malaria prophylaxis in those individuals who may be at increased risk for side effects.
format Article
id doaj-art-15fd0713f894422c926524c2c6fdfd8a
institution Kabale University
issn 2090-682X
2090-6838
language English
publishDate 2011-01-01
publisher Wiley
record_format Article
series Case Reports in Psychiatry
spelling doaj-art-15fd0713f894422c926524c2c6fdfd8a2025-08-20T03:54:24ZengWileyCase Reports in Psychiatry2090-682X2090-68382011-01-01201110.1155/2011/350417350417Severe Neuropsychiatric Reaction in a Deployed Military Member after Prophylactic MefloquineAlan L. Peterson0Robert A. Seegmiller1Libby S. Schindler2Department of Psychiatry, University of Texas Health Science Center, San Antonio, TX 78229, USA59th Medical Operations Squadron, Wilford Hall Medical Center, San Antonio, TX 78236, USA59th Medical Operations Squadron, Wilford Hall Medical Center, San Antonio, TX 78236, USARecent studies of military personnel who have deployed to Iraq and Afghanistan have reported a number of combat-related psychiatric disorders such as posttraumatic stress disorder, depression, and traumatic brain injury. This case report involves a 27-year-old male active-duty US military service member who developed severe depression, psychotic hallucinations, and neuropsychological sequelae following the prophylactic use of the antimalarial medication mefloquine hydrochloride. The patient had a recent history of depression and was taking antidepressant medications at the time of his deployment to the Middle East. Psychiatrists and other health care providers should be aware of the possible neuropsychiatric side effects of mefloquine in deployed military personnel and should consider the use of other medications for malaria prophylaxis in those individuals who may be at increased risk for side effects.http://dx.doi.org/10.1155/2011/350417
spellingShingle Alan L. Peterson
Robert A. Seegmiller
Libby S. Schindler
Severe Neuropsychiatric Reaction in a Deployed Military Member after Prophylactic Mefloquine
Case Reports in Psychiatry
title Severe Neuropsychiatric Reaction in a Deployed Military Member after Prophylactic Mefloquine
title_full Severe Neuropsychiatric Reaction in a Deployed Military Member after Prophylactic Mefloquine
title_fullStr Severe Neuropsychiatric Reaction in a Deployed Military Member after Prophylactic Mefloquine
title_full_unstemmed Severe Neuropsychiatric Reaction in a Deployed Military Member after Prophylactic Mefloquine
title_short Severe Neuropsychiatric Reaction in a Deployed Military Member after Prophylactic Mefloquine
title_sort severe neuropsychiatric reaction in a deployed military member after prophylactic mefloquine
url http://dx.doi.org/10.1155/2011/350417
work_keys_str_mv AT alanlpeterson severeneuropsychiatricreactioninadeployedmilitarymemberafterprophylacticmefloquine
AT robertaseegmiller severeneuropsychiatricreactioninadeployedmilitarymemberafterprophylacticmefloquine
AT libbysschindler severeneuropsychiatricreactioninadeployedmilitarymemberafterprophylacticmefloquine