Changes in Osteoblastic Bone Metastasis Detected Incidentally by Cone-Beam Computed Tomography: A Case Report
Introduction: Although cone-beam computed tomography (CBCT) is essential for tumor positioning in image-guided radiotherapy, its diagnostic application is limited by low image quality. This report highlights a case where CBCT unexpectedly detected osteoblastic bone metastasis during radio...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2025-03-01
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| Series: | Case Reports in Oncology |
| Online Access: | https://karger.com/article/doi/10.1159/000545252 |
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| Summary: | Introduction: Although cone-beam computed tomography (CBCT) is essential for tumor positioning in image-guided radiotherapy, its diagnostic application is limited by low image quality. This report highlights a case where CBCT unexpectedly detected osteoblastic bone metastasis during radiotherapy for prostate cancer. Case Presentation: A 65-year-old man with recurrent prostate cancer underwent postoperative intensity-modulated radiotherapy of 66 Gy in 33 fractions. Two months after treatment, an increase in prostate-specific antigen (PSA) levels led us to perform imaging that revealed a new osteoblastic metastasis in the left acetabulum. A retrospective review of the CBCT scans obtained during radiotherapy showed progressive osteoblastic changes that were not visible on pre-treatment imaging. Conclusion: The progressive changes in osteoblastic bone metastases on CBCT highlight its potential usefulness in daily monitoring and evaluation during radiotherapy. |
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| ISSN: | 1662-6575 |