Capturing protein communities by structural proteomics in a thermophilic eukaryote

Capturing protein communities by structural proteomics in a thermophilic eukaryote

Abstract The arrangement of proteins into complexes is a key organizational principle for many cellular functions. Although the topology of many complexes has been systematically analyzed in isolation, their molecular sociology in situ remains elusive. Here, we show that crude cellular extracts of a...

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Bibliographic Details
Main Authors: Panagiotis L Kastritis, Francis J O'Reilly, Thomas Bock, Yuanyue Li, Matt Z Rogon, Katarzyna Buczak, Natalie Romanov, Matthew J Betts, Khanh Huy Bui, Wim J Hagen, Marco L Hennrich, Marie‐Therese Mackmull, Juri Rappsilber, Robert B Russell, Peer Bork, Martin Beck, Anne‐Claude Gavin
Format: Article
Language:English
Published: Springer Nature 2017-07-01
Series:Molecular Systems Biology
Subjects:
computational modeling
cryo‐electron microscopy
fatty acid synthase
interaction proteomics
metabolon
Online Access:https://doi.org/10.15252/msb.20167412
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