Evaluation of intestinal tissue safety during the compression process of circular end-to-end anastomosis stapler based on finite element simulation

ObjectiveCurrently, there is no standardized finite element analysis method for investigating the safe compression range of circular end-to-end anastomosis stapler. This study aims to develop a finite element analysis framework based on stress thresholds and the volumetric distribution of tissue sta...

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Main Authors: Yuanda Zhou, Zhen Tan, Peishi Jiang, Yi Sun, Dewang Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1594969/full
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author Yuanda Zhou
Yuanda Zhou
Yuanda Zhou
Yuanda Zhou
Zhen Tan
Peishi Jiang
Yi Sun
Yi Sun
Yi Sun
Yi Sun
Dewang Wu
author_facet Yuanda Zhou
Yuanda Zhou
Yuanda Zhou
Yuanda Zhou
Zhen Tan
Peishi Jiang
Yi Sun
Yi Sun
Yi Sun
Yi Sun
Dewang Wu
author_sort Yuanda Zhou
collection DOAJ
description ObjectiveCurrently, there is no standardized finite element analysis method for investigating the safe compression range of circular end-to-end anastomosis stapler. This study aims to develop a finite element analysis framework based on stress thresholds and the volumetric distribution of tissue states, and to investigate the effects of tissue thickness and compression ratio on the risk of compression-induced injury during anastomosis. The evaluation is conducted by calculating the proportion of the volume of elements categorized as “effective fixation” or “damaged” based on equivalent stress.MethodsA disposable circular end-to-end anastomosis stapler was used as the reference model to create a 1:1 scale 3D model of the key components at the contact surface, including the anvil, staple cartridge, and cutting washer. Finite element models of intestinal tissue with varying thicknesses were established within the environment of the circular stapler. Different compression ratios were applied to analyze the stress distribution in the intestinal tissue.ResultsAcross experiments with intestinal tissues of all thicknesses, the safe compression ratio consistently centered around 60%. The maximum equivalent stress on the lower intestinal segment was always greater than that on the upper segment, while the average equivalent stress of the upper and lower intestinal segments exhibited a collinear distribution across experiments with varying tissue thickness. An increase in total tissue thickness positively contributed to the expansion of the safe compression range. In asymmetric tissue thickness models, the side with greater thickness demonstrated a broader safe compression range.ConclusionThe safe compression range of staplers is closely related to the properties and thickness of the tissue. This study provides a framework for simulating and determining the safe compression range of staplers.
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spelling doaj-art-15f505d537084639a6ec7979817fe0e52025-08-20T03:30:36ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-06-011310.3389/fbioe.2025.15949691594969Evaluation of intestinal tissue safety during the compression process of circular end-to-end anastomosis stapler based on finite element simulationYuanda Zhou0Yuanda Zhou1Yuanda Zhou2Yuanda Zhou3Zhen Tan4Peishi Jiang5Yi Sun6Yi Sun7Yi Sun8Yi Sun9Dewang Wu10Department of Colorectal Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, ChinaNankai University School of Medicine, Nankai University, Tianjin, ChinaThe Institute of Translational Medicine, Tianjin Union Medical Center of Nankai University, Tianjin, ChinaTianjin Institute of Coloproctology, Tianjin, ChinaNankai University School of Medicine, Nankai University, Tianjin, ChinaNankai University School of Medicine, Nankai University, Tianjin, ChinaDepartment of Colorectal Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, ChinaNankai University School of Medicine, Nankai University, Tianjin, ChinaThe Institute of Translational Medicine, Tianjin Union Medical Center of Nankai University, Tianjin, ChinaTianjin Institute of Coloproctology, Tianjin, ChinaDepartment of Anorectal Surgery, Gansu Provincial Hospital, Gansu Clinical Medical Research Center for Anorectal Diseases, Lanzhou, Gansu, ChinaObjectiveCurrently, there is no standardized finite element analysis method for investigating the safe compression range of circular end-to-end anastomosis stapler. This study aims to develop a finite element analysis framework based on stress thresholds and the volumetric distribution of tissue states, and to investigate the effects of tissue thickness and compression ratio on the risk of compression-induced injury during anastomosis. The evaluation is conducted by calculating the proportion of the volume of elements categorized as “effective fixation” or “damaged” based on equivalent stress.MethodsA disposable circular end-to-end anastomosis stapler was used as the reference model to create a 1:1 scale 3D model of the key components at the contact surface, including the anvil, staple cartridge, and cutting washer. Finite element models of intestinal tissue with varying thicknesses were established within the environment of the circular stapler. Different compression ratios were applied to analyze the stress distribution in the intestinal tissue.ResultsAcross experiments with intestinal tissues of all thicknesses, the safe compression ratio consistently centered around 60%. The maximum equivalent stress on the lower intestinal segment was always greater than that on the upper segment, while the average equivalent stress of the upper and lower intestinal segments exhibited a collinear distribution across experiments with varying tissue thickness. An increase in total tissue thickness positively contributed to the expansion of the safe compression range. In asymmetric tissue thickness models, the side with greater thickness demonstrated a broader safe compression range.ConclusionThe safe compression range of staplers is closely related to the properties and thickness of the tissue. This study provides a framework for simulating and determining the safe compression range of staplers.https://www.frontiersin.org/articles/10.3389/fbioe.2025.1594969/fullcircular end-to-end anastomosis staplercompression injuryfinite element analysiscompression ratioequivalent stress
spellingShingle Yuanda Zhou
Yuanda Zhou
Yuanda Zhou
Yuanda Zhou
Zhen Tan
Peishi Jiang
Yi Sun
Yi Sun
Yi Sun
Yi Sun
Dewang Wu
Evaluation of intestinal tissue safety during the compression process of circular end-to-end anastomosis stapler based on finite element simulation
Frontiers in Bioengineering and Biotechnology
circular end-to-end anastomosis stapler
compression injury
finite element analysis
compression ratio
equivalent stress
title Evaluation of intestinal tissue safety during the compression process of circular end-to-end anastomosis stapler based on finite element simulation
title_full Evaluation of intestinal tissue safety during the compression process of circular end-to-end anastomosis stapler based on finite element simulation
title_fullStr Evaluation of intestinal tissue safety during the compression process of circular end-to-end anastomosis stapler based on finite element simulation
title_full_unstemmed Evaluation of intestinal tissue safety during the compression process of circular end-to-end anastomosis stapler based on finite element simulation
title_short Evaluation of intestinal tissue safety during the compression process of circular end-to-end anastomosis stapler based on finite element simulation
title_sort evaluation of intestinal tissue safety during the compression process of circular end to end anastomosis stapler based on finite element simulation
topic circular end-to-end anastomosis stapler
compression injury
finite element analysis
compression ratio
equivalent stress
url https://www.frontiersin.org/articles/10.3389/fbioe.2025.1594969/full
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