Drug induced mortality: a multiple cause approach on Italian causes of death Register

<p><span>Background: </span>Drug-related mortality is a complex phenomenon that has several health, social and economic effects. In this paper trends of drug-induced mortality in Italy are analysed. Two approaches have been followed: the traditional analysis of the underlying cause...

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Main Authors: Francesco Grippo, Marilena Pappagallo, Alessandra Burgio, Roberta Crialesi
Format: Article
Language:English
Published: Milano University Press 2015-04-01
Series:Epidemiology, Biostatistics and Public Health
Online Access:http://ebph.it/article/view/11177
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author Francesco Grippo
Marilena Pappagallo
Alessandra Burgio
Roberta Crialesi
author_facet Francesco Grippo
Marilena Pappagallo
Alessandra Burgio
Roberta Crialesi
author_sort Francesco Grippo
collection DOAJ
description <p><span>Background: </span>Drug-related mortality is a complex phenomenon that has several health, social and economic effects. In this paper trends of drug-induced mortality in Italy are analysed. Two approaches have been followed: the traditional analysis of the underlying cause of death (UC) (data refers to the Istat mortality database from 1980 to 2011), and the multiple cause (MC)analysis, that is the analysis of all conditions reported on the death certificate (data for 2003-2011 period).</p><p><span>Methods: </span>Data presented in this paper are based on the Italian mortality register. The selection of Icd codes used for the analysis follows the definition of the European Monitoring Centre for Drugs and Drug Addiction. Using different indicators (crude and standardized rates, ratio multiple to underlying), the results obtained from the two approaches (UC and MC) have been compared. Moreover, as a measure of association between drug-related causes and specific conditions on the death certificate, an estimation of the age-standardized relative risk (RR) has been used.</p><p><span>Results: </span>In the years 2009-2011, the total number of certificates whit mention of drug use was 1,293, 60% higher than the number UC based. The groups of conditions more strongly associated with drug-related causes are the mental and behavioral disorders (especially alcohol consumption), viral hepatitis, cirrhosis and fibrosis of liver, AIDS and endocarditis.</p><p><span>Conclusions : </span>The analysis based on multiple cause approach shows, for the first time, a more detailed picture of the drug related death; it allows to better describe the mortality profiles and to re-evaluate  the contribution of a specific cause to death.</p>
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spelling doaj-art-15f0fb0af60f404eafee9293b5e10e722025-08-20T03:17:18ZengMilano University PressEpidemiology, Biostatistics and Public Health2282-09302015-04-0112110.2427/1117710393Drug induced mortality: a multiple cause approach on Italian causes of death RegisterFrancesco Grippo0Marilena Pappagallo1Alessandra Burgio2Roberta Crialesi3Italian National Institute of Statistics – Health and assistance service - Rome, ItalyItalian National Institute of Statistics – Health and assistance service - Rome, ItalyItalian National Institute of Statistics – Health and assistance service - Rome, ItalyItalian National Institute of Statistics – Health and assistance service - Rome, Italy<p><span>Background: </span>Drug-related mortality is a complex phenomenon that has several health, social and economic effects. In this paper trends of drug-induced mortality in Italy are analysed. Two approaches have been followed: the traditional analysis of the underlying cause of death (UC) (data refers to the Istat mortality database from 1980 to 2011), and the multiple cause (MC)analysis, that is the analysis of all conditions reported on the death certificate (data for 2003-2011 period).</p><p><span>Methods: </span>Data presented in this paper are based on the Italian mortality register. The selection of Icd codes used for the analysis follows the definition of the European Monitoring Centre for Drugs and Drug Addiction. Using different indicators (crude and standardized rates, ratio multiple to underlying), the results obtained from the two approaches (UC and MC) have been compared. Moreover, as a measure of association between drug-related causes and specific conditions on the death certificate, an estimation of the age-standardized relative risk (RR) has been used.</p><p><span>Results: </span>In the years 2009-2011, the total number of certificates whit mention of drug use was 1,293, 60% higher than the number UC based. The groups of conditions more strongly associated with drug-related causes are the mental and behavioral disorders (especially alcohol consumption), viral hepatitis, cirrhosis and fibrosis of liver, AIDS and endocarditis.</p><p><span>Conclusions : </span>The analysis based on multiple cause approach shows, for the first time, a more detailed picture of the drug related death; it allows to better describe the mortality profiles and to re-evaluate  the contribution of a specific cause to death.</p>http://ebph.it/article/view/11177
spellingShingle Francesco Grippo
Marilena Pappagallo
Alessandra Burgio
Roberta Crialesi
Drug induced mortality: a multiple cause approach on Italian causes of death Register
Epidemiology, Biostatistics and Public Health
title Drug induced mortality: a multiple cause approach on Italian causes of death Register
title_full Drug induced mortality: a multiple cause approach on Italian causes of death Register
title_fullStr Drug induced mortality: a multiple cause approach on Italian causes of death Register
title_full_unstemmed Drug induced mortality: a multiple cause approach on Italian causes of death Register
title_short Drug induced mortality: a multiple cause approach on Italian causes of death Register
title_sort drug induced mortality a multiple cause approach on italian causes of death register
url http://ebph.it/article/view/11177
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AT alessandraburgio druginducedmortalityamultiplecauseapproachonitaliancausesofdeathregister
AT robertacrialesi druginducedmortalityamultiplecauseapproachonitaliancausesofdeathregister