Thyroid Carcinoma Glycoproteins Express Altered <i>N</i>-Glycans with 3-O-Sulfated Galactose Residues

Thyroid Carcinoma Glycoproteins Express Altered <i>N</i>-Glycans with 3-O-Sulfated Galactose Residues

Aberrant protein glycosylation is a hallmark alteration of cancer and is highly associated with cancer progression. Papillary thyroid cancer (PTC) is the most common type of thyroid cancer, but the <i>N</i>-glycosylation of its glycoproteins has not been well characterized. In this work,...

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Bibliographic Details
Main Authors: Jordan M. Broekhuis, Dongli Lu, Rajindra P. Aryal, Yasuyuki Matsumoto, Lauren E. Pepi, Natalia Chaves, Jorge L. Gomez-Mayorga, Benjamin C. James, Richard D. Cummings
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
GlcNAc bisection
glycosylation
lectin histochemistry
mass spectrometry
papillary thyroid cancer
RNAseq
Online Access:https://www.mdpi.com/2218-273X/14/12/1482
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