High prevalence and diversity of Leptospira pathogenic serogroups in pigs, cows and free roaming dogs from undeserved rural communities in the coastal region of Ecuador

Leptospirosis is a zoonotic disease with global distribution but endemic to tropical regions that affects animal production systems. In Ecuador, leptospirosis is endemic with records of human outbreaks dated from more than one century ago, and where the role of animal reservoirs in the transmission...

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Main Authors: Solon Alberto Orlando, Naomi Mora-Jaramillo, Ariana León-Sosa, Fabiola Jiménez Valenzuela, Joselyn Calderon, Ariana Rivera, Emma Matamba, Ericka Sanchez, Gabriela Macias, Gabriela Martinez, Ana Piña, Juana Huartanga, Vicente Solis, Katherine Paez, Patricia Sumoy Velez, Manuel Gonzalez, Angel Sebastián Rodríguez-Pazmiño, Miguel Angel García-Bereguiain
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:One Health
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352771425001193
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author Solon Alberto Orlando
Naomi Mora-Jaramillo
Ariana León-Sosa
Fabiola Jiménez Valenzuela
Joselyn Calderon
Ariana Rivera
Emma Matamba
Ericka Sanchez
Gabriela Macias
Gabriela Martinez
Ana Piña
Juana Huartanga
Vicente Solis
Katherine Paez
Patricia Sumoy Velez
Manuel Gonzalez
Angel Sebastián Rodríguez-Pazmiño
Miguel Angel García-Bereguiain
author_facet Solon Alberto Orlando
Naomi Mora-Jaramillo
Ariana León-Sosa
Fabiola Jiménez Valenzuela
Joselyn Calderon
Ariana Rivera
Emma Matamba
Ericka Sanchez
Gabriela Macias
Gabriela Martinez
Ana Piña
Juana Huartanga
Vicente Solis
Katherine Paez
Patricia Sumoy Velez
Manuel Gonzalez
Angel Sebastián Rodríguez-Pazmiño
Miguel Angel García-Bereguiain
author_sort Solon Alberto Orlando
collection DOAJ
description Leptospirosis is a zoonotic disease with global distribution but endemic to tropical regions that affects animal production systems. In Ecuador, leptospirosis is endemic with records of human outbreaks dated from more than one century ago, and where the role of animal reservoirs in the transmission dynamics is not well understood. In this study, we carried out a serological surveillance by Microagglutination Test with a panel of 24 serovars for 545 animals represented by pigs and cows, and free roaming dogs from undeserved rural communities in the province of Guayas (Coastal Region of Ecuador). Our results underscore a wide diversity of pathogenic serogroups with high prevalence across animal species including Bataviae, Australis, Pomoma, Canicola, Djasiman or Grippotyphosa. Moreover, a high seroprevalence for antibodies against Leptospira was found across all the species analyzed, with values of 87 % (CI95 %: 70,6–100) in dogs, 66.7 % (CI95 %: 53,6-79,7) in cows, and 100 % (CI95 %: 80,4–100) in pigs. Our results confirm previous finding about the complex epidemiology of leptospirosis in Ecuador, comprising multiples serogroups and animal reservoirs. Therefore, we strongly recommend incorporating an integrative One Health approach for the surveillance and prevention of leptospirosis in Ecuador.
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spelling doaj-art-15e3c46955ff4f8c9abe67e2192d2ce42025-08-20T02:36:02ZengElsevierOne Health2352-77142025-06-012010108310.1016/j.onehlt.2025.101083High prevalence and diversity of Leptospira pathogenic serogroups in pigs, cows and free roaming dogs from undeserved rural communities in the coastal region of EcuadorSolon Alberto Orlando0Naomi Mora-Jaramillo1Ariana León-Sosa2Fabiola Jiménez Valenzuela3Joselyn Calderon4Ariana Rivera5Emma Matamba6Ericka Sanchez7Gabriela Macias8Gabriela Martinez9Ana Piña10Juana Huartanga11Vicente Solis12Katherine Paez13Patricia Sumoy Velez14Manuel Gonzalez15Angel Sebastián Rodríguez-Pazmiño16Miguel Angel García-Bereguiain17Instituto Nacional de Salud Pública en Investigación, Guayaquil, Ecuador; Universidad Espiritu Santo, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorUniversidad Católica Santiago de Guayaquil, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, Ecuador; Universidad Ecotec, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorInstituto Nacional de Salud Pública en Investigación, Guayaquil, EcuadorOne Health Research Group, Universidad de Las Américas, Quito 170516, EcuadorOne Health Research Group, Universidad de Las Américas, Quito 170516, Ecuador; Corresponding author.Leptospirosis is a zoonotic disease with global distribution but endemic to tropical regions that affects animal production systems. In Ecuador, leptospirosis is endemic with records of human outbreaks dated from more than one century ago, and where the role of animal reservoirs in the transmission dynamics is not well understood. In this study, we carried out a serological surveillance by Microagglutination Test with a panel of 24 serovars for 545 animals represented by pigs and cows, and free roaming dogs from undeserved rural communities in the province of Guayas (Coastal Region of Ecuador). Our results underscore a wide diversity of pathogenic serogroups with high prevalence across animal species including Bataviae, Australis, Pomoma, Canicola, Djasiman or Grippotyphosa. Moreover, a high seroprevalence for antibodies against Leptospira was found across all the species analyzed, with values of 87 % (CI95 %: 70,6–100) in dogs, 66.7 % (CI95 %: 53,6-79,7) in cows, and 100 % (CI95 %: 80,4–100) in pigs. Our results confirm previous finding about the complex epidemiology of leptospirosis in Ecuador, comprising multiples serogroups and animal reservoirs. Therefore, we strongly recommend incorporating an integrative One Health approach for the surveillance and prevention of leptospirosis in Ecuador.http://www.sciencedirect.com/science/article/pii/S2352771425001193ZoonosisLeptospirosisMATBackyard animalsEcuadorOne health
spellingShingle Solon Alberto Orlando
Naomi Mora-Jaramillo
Ariana León-Sosa
Fabiola Jiménez Valenzuela
Joselyn Calderon
Ariana Rivera
Emma Matamba
Ericka Sanchez
Gabriela Macias
Gabriela Martinez
Ana Piña
Juana Huartanga
Vicente Solis
Katherine Paez
Patricia Sumoy Velez
Manuel Gonzalez
Angel Sebastián Rodríguez-Pazmiño
Miguel Angel García-Bereguiain
High prevalence and diversity of Leptospira pathogenic serogroups in pigs, cows and free roaming dogs from undeserved rural communities in the coastal region of Ecuador
One Health
Zoonosis
Leptospirosis
MAT
Backyard animals
Ecuador
One health
title High prevalence and diversity of Leptospira pathogenic serogroups in pigs, cows and free roaming dogs from undeserved rural communities in the coastal region of Ecuador
title_full High prevalence and diversity of Leptospira pathogenic serogroups in pigs, cows and free roaming dogs from undeserved rural communities in the coastal region of Ecuador
title_fullStr High prevalence and diversity of Leptospira pathogenic serogroups in pigs, cows and free roaming dogs from undeserved rural communities in the coastal region of Ecuador
title_full_unstemmed High prevalence and diversity of Leptospira pathogenic serogroups in pigs, cows and free roaming dogs from undeserved rural communities in the coastal region of Ecuador
title_short High prevalence and diversity of Leptospira pathogenic serogroups in pigs, cows and free roaming dogs from undeserved rural communities in the coastal region of Ecuador
title_sort high prevalence and diversity of leptospira pathogenic serogroups in pigs cows and free roaming dogs from undeserved rural communities in the coastal region of ecuador
topic Zoonosis
Leptospirosis
MAT
Backyard animals
Ecuador
One health
url http://www.sciencedirect.com/science/article/pii/S2352771425001193
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