HIV-1 and Antiretroviral Therapy Modulate HERV Pol and Syncytin Gene Expression in Mothers and Newborns

HIV-1 and Antiretroviral Therapy Modulate HERV Pol and Syncytin Gene Expression in Mothers and Newborns

Background: Human endogenous retroviruses (HERVs) are remnants of ancestral retroviral infections integrated into the human genome, some of which maintain a residual active expression and retain physiological relevance. HIV-1 infection and antiretroviral therapy (ART) are known to modulate HERV expr...

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Bibliographic Details
Main Authors: Anna Pau, Ilaria Galliano, Stefano Gambarino, Anna Clemente, Paola Montanari, Cristina Calvi, Pier-Angelo Tovo, Massimiliano Bergallo
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Microbiology Research
Subjects:
HERVs
HIV-1
antiretroviral therapy
ART
mothers
Online Access:https://www.mdpi.com/2036-7481/16/6/116
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