Type 2 Diabetes, PUFAs, and Vitamin D: Their Relation to Inflammation
Chronic diseases have become one of the most important public health problems, due to their high costs for treatment and prevention. Until now, researchers have considered that the etiology of Type 2 diabetes mellitus (T2DM) is multifactorial. Recently, the study of the innate immune system has offe...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2014/860703 |
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| author | Ana L. Guadarrama-López Roxana Valdés-Ramos Beatríz E. Martínez-Carrillo |
| author_facet | Ana L. Guadarrama-López Roxana Valdés-Ramos Beatríz E. Martínez-Carrillo |
| author_sort | Ana L. Guadarrama-López |
| collection | DOAJ |
| description | Chronic diseases have become one of the most important public health problems, due to their high costs for treatment and prevention. Until now, researchers have considered that the etiology of Type 2 diabetes mellitus (T2DM) is multifactorial. Recently, the study of the innate immune system has offered an explanation model of the pathogenesis of T2DM. On the other hand, there is evidence about the beneficial effect of polyunsaturated fatty acids (PUFA) n-3 and n-6 in patients with chronic inflammatory diseases including diabetes. Furthermore, high vitamin D plasmatic concentrations have been associated with the best performance of pancreatic β cells and the improving of this disease. In conclusion, certain fatty acids in the adequate proportion as well as 25-hydroxivitamin D can modulate the inflammatory response in diabetic people, modifying the evolution of this disease. |
| format | Article |
| id | doaj-art-15c1086388bf404a93e3b66eff7e7f47 |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-15c1086388bf404a93e3b66eff7e7f472025-02-03T05:51:37ZengWileyJournal of Immunology Research2314-88612314-71562014-01-01201410.1155/2014/860703860703Type 2 Diabetes, PUFAs, and Vitamin D: Their Relation to InflammationAna L. Guadarrama-López0Roxana Valdés-Ramos1Beatríz E. Martínez-Carrillo2Center for Research and Graduate Studies in Health Sciences, Faculty of Medicine, Autonomous University of the State of Mexico, Paseo Tollocan Esquina, Jesús Carranza, Col. Moderna de la Cruz Toluca, 50180 México, MEX, MexicoCenter for Research and Graduate Studies in Health Sciences, Faculty of Medicine, Autonomous University of the State of Mexico, Paseo Tollocan Esquina, Jesús Carranza, Col. Moderna de la Cruz Toluca, 50180 México, MEX, MexicoCenter for Research and Graduate Studies in Health Sciences, Faculty of Medicine, Autonomous University of the State of Mexico, Paseo Tollocan Esquina, Jesús Carranza, Col. Moderna de la Cruz Toluca, 50180 México, MEX, MexicoChronic diseases have become one of the most important public health problems, due to their high costs for treatment and prevention. Until now, researchers have considered that the etiology of Type 2 diabetes mellitus (T2DM) is multifactorial. Recently, the study of the innate immune system has offered an explanation model of the pathogenesis of T2DM. On the other hand, there is evidence about the beneficial effect of polyunsaturated fatty acids (PUFA) n-3 and n-6 in patients with chronic inflammatory diseases including diabetes. Furthermore, high vitamin D plasmatic concentrations have been associated with the best performance of pancreatic β cells and the improving of this disease. In conclusion, certain fatty acids in the adequate proportion as well as 25-hydroxivitamin D can modulate the inflammatory response in diabetic people, modifying the evolution of this disease.http://dx.doi.org/10.1155/2014/860703 |
| spellingShingle | Ana L. Guadarrama-López Roxana Valdés-Ramos Beatríz E. Martínez-Carrillo Type 2 Diabetes, PUFAs, and Vitamin D: Their Relation to Inflammation Journal of Immunology Research |
| title | Type 2 Diabetes, PUFAs, and Vitamin D: Their Relation to Inflammation |
| title_full | Type 2 Diabetes, PUFAs, and Vitamin D: Their Relation to Inflammation |
| title_fullStr | Type 2 Diabetes, PUFAs, and Vitamin D: Their Relation to Inflammation |
| title_full_unstemmed | Type 2 Diabetes, PUFAs, and Vitamin D: Their Relation to Inflammation |
| title_short | Type 2 Diabetes, PUFAs, and Vitamin D: Their Relation to Inflammation |
| title_sort | type 2 diabetes pufas and vitamin d their relation to inflammation |
| url | http://dx.doi.org/10.1155/2014/860703 |
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