Pseudomonas aeruginosa Isolates from Water Samples of the Gulf of Mexico Show Similar Virulence Properties but Different Antibiotic Susceptibility Profiles than Clinical Isolates

Pseudomonas aeruginosa is an opportunistic pathogen found in a wide variety of environments, including soil, water, and habitats associated with animals, humans, and plants. From a One Health perspective, which recognizes the interconnectedness of human, animal, and environmental health, it is impor...

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Main Authors: Luis E. Romero-González, Luis F. Montelongo-Martínez, Abigail González-Valdez, Sara E. Quiroz-Morales, Miguel Cocotl-Yañez, Rafael Franco-Cendejas, Gloria Soberón-Chávez, Liliana Pardo-López, Víctor H. Bustamante
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:International Journal of Microbiology
Online Access:http://dx.doi.org/10.1155/2024/6959403
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author Luis E. Romero-González
Luis F. Montelongo-Martínez
Abigail González-Valdez
Sara E. Quiroz-Morales
Miguel Cocotl-Yañez
Rafael Franco-Cendejas
Gloria Soberón-Chávez
Liliana Pardo-López
Víctor H. Bustamante
author_facet Luis E. Romero-González
Luis F. Montelongo-Martínez
Abigail González-Valdez
Sara E. Quiroz-Morales
Miguel Cocotl-Yañez
Rafael Franco-Cendejas
Gloria Soberón-Chávez
Liliana Pardo-López
Víctor H. Bustamante
author_sort Luis E. Romero-González
collection DOAJ
description Pseudomonas aeruginosa is an opportunistic pathogen found in a wide variety of environments, including soil, water, and habitats associated with animals, humans, and plants. From a One Health perspective, which recognizes the interconnectedness of human, animal, and environmental health, it is important to study the virulence characteristics and antibiotic susceptibility of environmental bacteria. In this study, we compared the virulence properties and the antibiotic resistance profiles of seven isolates collected from the Gulf of Mexico with those of seven clinical strains of P. aeruginosa. Our results indicate that the marine and clinical isolates tested exhibit similar virulence properties; they expressed different virulence factors and were able to kill Galleria mellonella larvae, an animal model commonly used to analyze the pathogenicity of many bacteria, including P. aeruginosa. In contrast, the clinical strains showed higher antibiotic resistance than the marine isolates. Consistently, the clinical strains exhibited a higher prevalence of class 1 integron, an indicator of anthropogenic impact, compared with the marine isolates. Thus, our results indicate that the P. aeruginosa marine strains analyzed in this study, isolated from the Gulf of Mexico, have similar virulence properties, but lower antibiotic resistance, than those from hospitals.
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issn 1687-9198
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publisher Wiley
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spelling doaj-art-15bc03e64aa548b88f8418b3cd83afe32025-08-20T02:02:41ZengWileyInternational Journal of Microbiology1687-91982024-01-01202410.1155/2024/6959403Pseudomonas aeruginosa Isolates from Water Samples of the Gulf of Mexico Show Similar Virulence Properties but Different Antibiotic Susceptibility Profiles than Clinical IsolatesLuis E. Romero-González0Luis F. Montelongo-Martínez1Abigail González-Valdez2Sara E. Quiroz-Morales3Miguel Cocotl-Yañez4Rafael Franco-Cendejas5Gloria Soberón-Chávez6Liliana Pardo-López7Víctor H. Bustamante8Departamento de Microbiología MolecularDepartamento de Microbiología y ParasitologíaDepartamento de Biología Molecular y BiotecnologíaDepartamento de Biología Molecular y BiotecnologíaDepartamento de Microbiología y ParasitologíaInstituto Nacional de Rehabilitación “Luis Guillermo Ibarra Ibarra,” Ciudad de MéxicoDepartamento de Biología Molecular y BiotecnologíaDepartamento de Microbiología MolecularDepartamento de Microbiología MolecularPseudomonas aeruginosa is an opportunistic pathogen found in a wide variety of environments, including soil, water, and habitats associated with animals, humans, and plants. From a One Health perspective, which recognizes the interconnectedness of human, animal, and environmental health, it is important to study the virulence characteristics and antibiotic susceptibility of environmental bacteria. In this study, we compared the virulence properties and the antibiotic resistance profiles of seven isolates collected from the Gulf of Mexico with those of seven clinical strains of P. aeruginosa. Our results indicate that the marine and clinical isolates tested exhibit similar virulence properties; they expressed different virulence factors and were able to kill Galleria mellonella larvae, an animal model commonly used to analyze the pathogenicity of many bacteria, including P. aeruginosa. In contrast, the clinical strains showed higher antibiotic resistance than the marine isolates. Consistently, the clinical strains exhibited a higher prevalence of class 1 integron, an indicator of anthropogenic impact, compared with the marine isolates. Thus, our results indicate that the P. aeruginosa marine strains analyzed in this study, isolated from the Gulf of Mexico, have similar virulence properties, but lower antibiotic resistance, than those from hospitals.http://dx.doi.org/10.1155/2024/6959403
spellingShingle Luis E. Romero-González
Luis F. Montelongo-Martínez
Abigail González-Valdez
Sara E. Quiroz-Morales
Miguel Cocotl-Yañez
Rafael Franco-Cendejas
Gloria Soberón-Chávez
Liliana Pardo-López
Víctor H. Bustamante
Pseudomonas aeruginosa Isolates from Water Samples of the Gulf of Mexico Show Similar Virulence Properties but Different Antibiotic Susceptibility Profiles than Clinical Isolates
International Journal of Microbiology
title Pseudomonas aeruginosa Isolates from Water Samples of the Gulf of Mexico Show Similar Virulence Properties but Different Antibiotic Susceptibility Profiles than Clinical Isolates
title_full Pseudomonas aeruginosa Isolates from Water Samples of the Gulf of Mexico Show Similar Virulence Properties but Different Antibiotic Susceptibility Profiles than Clinical Isolates
title_fullStr Pseudomonas aeruginosa Isolates from Water Samples of the Gulf of Mexico Show Similar Virulence Properties but Different Antibiotic Susceptibility Profiles than Clinical Isolates
title_full_unstemmed Pseudomonas aeruginosa Isolates from Water Samples of the Gulf of Mexico Show Similar Virulence Properties but Different Antibiotic Susceptibility Profiles than Clinical Isolates
title_short Pseudomonas aeruginosa Isolates from Water Samples of the Gulf of Mexico Show Similar Virulence Properties but Different Antibiotic Susceptibility Profiles than Clinical Isolates
title_sort pseudomonas aeruginosa isolates from water samples of the gulf of mexico show similar virulence properties but different antibiotic susceptibility profiles than clinical isolates
url http://dx.doi.org/10.1155/2024/6959403
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