NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption

Abstract Applying the orthogonal principle for distinguishable second near‐infrared (NIR‐II) emissions has brought new dimensions for ratio fluorescence imaging (RFI) detection and information encryption, deepening the tissue detection depth and improving signal‐to‐noise ratio and information securi...

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Main Authors: Qiqing Li, Yuanping Huang, Haoyu Zhu, Yaqi Zhu, Yuexi Yi, Xiaodan Li, Haoran Chen, Bin Li, Dabing Li, Yulei Chang
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
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Online Access:https://doi.org/10.1002/advs.202408097
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author Qiqing Li
Yuanping Huang
Haoyu Zhu
Yaqi Zhu
Yuexi Yi
Xiaodan Li
Haoran Chen
Bin Li
Dabing Li
Yulei Chang
author_facet Qiqing Li
Yuanping Huang
Haoyu Zhu
Yaqi Zhu
Yuexi Yi
Xiaodan Li
Haoran Chen
Bin Li
Dabing Li
Yulei Chang
author_sort Qiqing Li
collection DOAJ
description Abstract Applying the orthogonal principle for distinguishable second near‐infrared (NIR‐II) emissions has brought new dimensions for ratio fluorescence imaging (RFI) detection and information encryption, deepening the tissue detection depth and improving signal‐to‐noise ratio and information security. However, the orthogonal NIR‐II emissions underlying these advanced optical applications have been reported only in heterogeneous structures and mixtures, limiting their practicality and potential impact. Herein, NIR‐I‐activated orthogonal NIR‐IIb/c (1530/1825 nm) emissions nanoparticles (ONNPs) are developed by spatially separated doping of Tm3+ and Er3+ emitter upon switching 808 and 980 nm excitations. RFI techniques and orthogonal NIR‐II emission ONNPs are used to demonstrate vessel depth detection based on wavelength‐dependent optical attenuation properties in tissue. The superiority of the optical coding and encoding process in a 4 × 1 binary matrix is demonstrated for anticounterfeiting and decryption imaging of quick‐response (QR) code for information storage. The research progress of this NIR‐II orthogonal emissions probe will drive the development of biomedical sensing, imaging safety, and future biophotonics technologies.
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publishDate 2024-11-01
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spelling doaj-art-15b1f08d7bae461c88fad9fcd75651ee2025-08-20T01:52:38ZengWileyAdvanced Science2198-38442024-11-011144n/an/a10.1002/advs.202408097NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information EncryptionQiqing Li0Yuanping Huang1Haoyu Zhu2Yaqi Zhu3Yuexi Yi4Xiaodan Li5Haoran Chen6Bin Li7Dabing Li8Yulei Chang9Key Laboratory of Luminescence Science and Technology Chinese Academy of Sciences & State Key Laboratory of Luminescence Science and Applications Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences Changchun Jilin 130033 ChinaDepartment of Respiratory Medicine The First Hospital of Jilin University Changchun Jilin 130033 ChinaKey Laboratory of Luminescence Science and Technology Chinese Academy of Sciences & State Key Laboratory of Luminescence Science and Applications Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences Changchun Jilin 130033 ChinaKey Laboratory of Luminescence Science and Technology Chinese Academy of Sciences & State Key Laboratory of Luminescence Science and Applications Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences Changchun Jilin 130033 ChinaKey Laboratory of Luminescence Science and Technology Chinese Academy of Sciences & State Key Laboratory of Luminescence Science and Applications Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences Changchun Jilin 130033 ChinaDepartment of Respiratory Medicine The First Hospital of Jilin University Changchun Jilin 130033 ChinaKey Laboratory of Luminescence Science and Technology Chinese Academy of Sciences & State Key Laboratory of Luminescence Science and Applications Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences Changchun Jilin 130033 ChinaKey Laboratory of Luminescence Science and Technology Chinese Academy of Sciences & State Key Laboratory of Luminescence Science and Applications Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences Changchun Jilin 130033 ChinaKey Laboratory of Luminescence Science and Technology Chinese Academy of Sciences & State Key Laboratory of Luminescence Science and Applications Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences Changchun Jilin 130033 ChinaKey Laboratory of Luminescence Science and Technology Chinese Academy of Sciences & State Key Laboratory of Luminescence Science and Applications Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences Changchun Jilin 130033 ChinaAbstract Applying the orthogonal principle for distinguishable second near‐infrared (NIR‐II) emissions has brought new dimensions for ratio fluorescence imaging (RFI) detection and information encryption, deepening the tissue detection depth and improving signal‐to‐noise ratio and information security. However, the orthogonal NIR‐II emissions underlying these advanced optical applications have been reported only in heterogeneous structures and mixtures, limiting their practicality and potential impact. Herein, NIR‐I‐activated orthogonal NIR‐IIb/c (1530/1825 nm) emissions nanoparticles (ONNPs) are developed by spatially separated doping of Tm3+ and Er3+ emitter upon switching 808 and 980 nm excitations. RFI techniques and orthogonal NIR‐II emission ONNPs are used to demonstrate vessel depth detection based on wavelength‐dependent optical attenuation properties in tissue. The superiority of the optical coding and encoding process in a 4 × 1 binary matrix is demonstrated for anticounterfeiting and decryption imaging of quick‐response (QR) code for information storage. The research progress of this NIR‐II orthogonal emissions probe will drive the development of biomedical sensing, imaging safety, and future biophotonics technologies.https://doi.org/10.1002/advs.202408097lanthanidesNIR‐IIencryptionorthogonal emissionratiometric fluorescence imaging
spellingShingle Qiqing Li
Yuanping Huang
Haoyu Zhu
Yaqi Zhu
Yuexi Yi
Xiaodan Li
Haoran Chen
Bin Li
Dabing Li
Yulei Chang
NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption
Advanced Science
lanthanides
NIR‐II
encryption
orthogonal emission
ratiometric fluorescence imaging
title NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption
title_full NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption
title_fullStr NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption
title_full_unstemmed NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption
title_short NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption
title_sort nir i activated orthogonal nir iib c emissions in a lanthanide doped nanoparticle for fluorescence imaging and information encryption
topic lanthanides
NIR‐II
encryption
orthogonal emission
ratiometric fluorescence imaging
url https://doi.org/10.1002/advs.202408097
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