Quantitative determination of cyclic guanosine monoposphate (c-GMP) in rat tissues using liquid chromatography and tandem mass spectrometry

Quantitative determination of cyclic guanosine monoposphate (c-GMP) in rat tissues using liquid chromatography and tandem mass spectrometry

Relevance. Cyclic 3′,5′-guanosine monophosphate is a secondary intracellular messenger that plays a key role in many physiological processes.Quantitative determination of the level of c-GMP in the tissues of laboratory animals is an urgent task of experimental pharmacology and physiology.Purpose of...

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Bibliographic Details
Main Authors: N. S. Popov, V. Yu. Balabanyan, N. Yu. Kolgina, G. A. Petrov, S. A. Donskov, I. B. Atadzhanov
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2023-11-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
hplc-ms/ms
tandem mass spectrometry
guanosine monophosphate
c-gmp
Online Access:https://www.pharmacokinetica.ru/jour/article/view/379
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